数量	产品目录编号	订购说明	数量 / 包装	公开价
			96-Well Plate

数量	产品目录编号	订购说明	数量 / 包装	公开价
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

420127 Sigma-AldrichInSolution™ Jasplakinolide, Jaspis johnstoni - Calbiochem

InSolution™ Jasplakinolide, Jaspis johnstoni, CAS 102396-24-7, is a 1 mM solution of Jasplakinolide, Jaspis johnstoni in DMSO. Acts as a potent inducer of actin polymerization and stabilization.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet
Citations

Primary Target: F-actin

Recommended Products

概述

Replacement Information

重要规格表

Empirical Formula
C₃₆H₄₅BrN₄O₆

价格及供货情况

产品目录编号	库存情况	包装	数量 / 包装	价格	数量
420127-50UGCN	正在查询供货情况...... — 目前缺货有货停产少量现货供货情况有待确认登录查看库存有货目前缺货有货其余：另行通知其余：另行通知另行通知联系客户服务 Contact Customer Service 联系客户服务联系客户服务	塑胶安瓿;塑胶针药瓶	50 μg	正在检索价格...... 无法检索价格。最小订购数量为倍数 Maximum Quantity is 以订单确认为准更多信息您节约了 ()。 — Request Pricing 登录查看价格	查看库存情况 —	添加到收藏夹添加到收藏夹添加到我的收藏夹

Description
Catalogue Number	420127
Brand Family	Calbiochem®

References
References	Rosado, J.A., et al. 2000. J. Biol. Chem. 275, 7527. Posey, S.C., and Bierer, B.E. 1999. J. Biol. Chem. 274, 4259. Senderowicz, A.M., et al. 1995. J. Natl. Cancer Inst. 87, 46. Bubb, M.R., et al. 1994. J. Biol. Chem. 269, 14869. Scott, V.R., et al. 1988. Antimicrob. Agents Chemother. 32, 1154.

Product Information
ATP Competitive	N
Form	Liquid
Formulation	A 1 mM (50 µg/71 µl) solution of Jasplakinolide, Jaspis johnstoni (Cat. No. 420107) in DMSO.
Hill Formula	C₃₆H₄₅BrN₄O₆
Chemical formula	C₃₆H₄₅BrN₄O₆
Hygroscopic	Hygroscopic
Reversible	N
Structure formula Image
Quality Level	MQ100

Applications
Application	InSolution™ Jasplakinolide, Jaspis johnstoni, CAS 102396-24-7, is a 1 mM solution of Jasplakinolide, Jaspis johnstoni in DMSO. Acts as a potent inducer of actin polymerization and stabilization.

Biological Information
Primary Target	F-actin
Primary Target IC<sub>50</sub>	Kd = 15 nM for actin binding
Purity	≥90% by HPLC

Physicochemical Information
Cell permeable	N

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Shipped with Blue Ice or with Dry Ice
Toxicity	Harmful
Storage	-20°C
Protect from Light	Protect from light
Hygroscopic	Hygroscopic
Do not freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-20°C).

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
420127-50UGCN	04055977188059

Documentation

InSolution™ Jasplakinolide, Jaspis johnstoni - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

InSolution™ Jasplakinolide, Jaspis johnstoni - Calbiochem 分析证书

标题	批号
420127	输入批号

参考

参考信息概述
Rosado, J.A., et al. 2000. J. Biol. Chem. 275, 7527. Posey, S.C., and Bierer, B.E. 1999. J. Biol. Chem. 274, 4259. Senderowicz, A.M., et al. 1995. J. Natl. Cancer Inst. 87, 46. Bubb, M.R., et al. 1994. J. Biol. Chem. 269, 14869. Scott, V.R., et al. 1988. Antimicrob. Agents Chemother. 32, 1154.

引用

标题

Markus Utech, et al. (2005) Mechanism of IFN-γ-Induced Endocytosis of Tight Junction Proteins: Mysoin II-Dependent Vacuolarization of the Apical Plasma Membrane. Molecular Biology of the Cell 16, 5040-5052.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	17-March-2008 JSW
Description	A cell-permeable F-actin probe. This macrocyclic cyclodepsipeptide, isolated from the marine sponge Jaspis johnstoni, is a potent inducer of actin polymerization and stabilization in vitro. It competes with Phalloidin (Cat. No. 516640) for actin binding (K_d = 15 nM) and enhances apoptosis induced by interleukin 2 (IL-2) deprivation. Also displays fungicidal, insecticidal, and anticancer properties.
Form	Liquid
Formulation	A 1 mM (50 µg/71 µl) solution of Jasplakinolide, Jaspis johnstoni (Cat. No. 420107) in DMSO.
Intert gas (Yes/No)	Packaged under inert gas
Chemical formula	C₃₆H₄₅BrN₄O₆
Structure formula
Purity	≥90% by HPLC
Storage	Protect from light -20°C Hygroscopic
Do Not Freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-20°C).
Toxicity	Harmful
References	Rosado, J.A., et al. 2000. J. Biol. Chem. 275, 7527. Posey, S.C., and Bierer, B.E. 1999. J. Biol. Chem. 274, 4259. Senderowicz, A.M., et al. 1995. J. Natl. Cancer Inst. 87, 46. Bubb, M.R., et al. 1994. J. Biol. Chem. 269, 14869. Scott, V.R., et al. 1988. Antimicrob. Agents Chemother. 32, 1154.
Citation	Markus Utech, et al. (2005) Mechanism of IFN-γ-Induced Endocytosis of Tight Junction Proteins: Mysoin II-Dependent Vacuolarization of the Apical Plasma Membrane. Molecular Biology of the Cell 16, 5040-5052.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Extracellular Matrix, Adhesion and Cytoskeletal Research Tools

此产品已添加到您的购物车。