407602 Sigma-AldrichInSolution™ Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor - CAS 509093-47-4 - Calbiochem
The Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor controls the activity of Interleukin-1 Receptor-Associated-Kinase-1/4. Primarily used for Phosphorylation & Dephosphorylation apps.
More>> The Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor controls the activity of Interleukin-1 Receptor-Associated-Kinase-1/4. Primarily used for Phosphorylation & Dephosphorylation apps. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
同义词: N-(2-Morpholinylethyl)-2-(3-nitrobenzoylamido)-benzimidazole, N-(1-(2-morpholinoethyl)-1H-benzo[d]imidazol-2-yl)-3-nitrobenzamide
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概述
重要规格表
| CAS # | Empirical Formula |
|---|---|
| 509093-47-4 | C₂₀H₂₁N₅O₄ |
价格及供货情况
| 产品目录编号 | 库存情况 | 包装 | 数量 / 包装 | 价格 | 数量 | |
|---|---|---|---|---|---|---|
| 407602-5MGCN |
|
玻璃瓶 | 5 mg |
|
— |
| Description | |
|---|---|
| Overview | A cell-permeable benzimidazole compound that acts as a potent and selective inhibitor of interleukin-1 receptor-associated kinases (IC50 = 300 nM and 200 nM for IRAK-1 and -4). Shown to exhibit little activity against a panel of 27 other kinases (IC50 >10 µM), including lck and src. The solid form of this compound (Cat. No. 407601) is also available. |
| Catalogue Number | 407602 |
| Brand Family | Calbiochem® |
| Synonyms | N-(2-Morpholinylethyl)-2-(3-nitrobenzoylamido)-benzimidazole, N-(1-(2-morpholinoethyl)-1H-benzo[d]imidazol-2-yl)-3-nitrobenzamide |
| Product Information | |
|---|---|
| CAS number | 509093-47-4 |
| Form | Liquid |
| Formulation | A 25 mM (5 mg/506 µL) solution of Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor (Cat. No. 407601) in DMSO. |
| Hill Formula | C₂₀H₂₁N₅O₄ |
| Hygroscopic | Hygroscopic |
| Reversible | Y |
| Structure formula Image | |
| Quality Level | MQ100 |
| Biological Information | |
|---|---|
| Primary Target | IRAK-1/4 |
| Primary Target IC<sub>50</sub> | 300 nM and 200 nM for IRAK-1 and -4 |
| Purity | ≥98% by HPLC |
| Safety Information | |
|---|---|
| R Phrase | R: 36/38 Irritating to eyes and skin. |
| Packaging Information | |
|---|---|
| Packaged under inert gas | Packaged under inert gas |
| Global Trade Item Number | |
|---|---|
| 产品目录编号 | GTIN |
| 407602-5MGCN | 04055977211306 |