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401020
Sigma-AldrichImiquimod - CAS 99011-02-6 - Calbiochem
An imidazoquinoline compound that acts as a potent immunomodulator and displays anti-angiogenic, anti-viral and anti-inflammatory properties.
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Imiquimod - CAS 99011-02-6 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
An imidazoquinoline compound that acts as a potent immunomodulator and displays anti-angiogenic, anti-viral and anti-inflammatory properties. Reported to bind to the cell surface receptor, TLR7 (toll-like receptor 7), and induce the secretion of several pro-inflammatory cytokines and chemokines both in vitro and in vivo.
Toxic if swallowed. Irritating to eyes, respiratory system and skin.
S Phrase
S: 26-45
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Product Usage Statements
Storage and Shipping Information
Ship Code
Ambient Temperature Only
Toxicity
Toxic
Hazardous Materials Attention:
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage
+2°C to +8°C
Protect from Light
Protect from light
Do not freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Upon thawing, warming may be required to resolubilize precipitated product.
Majewski, S., et al. 2005. Int. J. Dermatol.44, 14. Gibson, S.J., et al. 2002. Cell. Immunol.218, 74. Hemmi, H., et al. 2002. Nat. Immunol.3, 196. Megyeri, K., et al. 1995. Mol. Cell. Biol.15, 2207.
数据表
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
An imidazoquinoline compound that acts as a potent immunomodulator and displays anti-angiogenic, anti-viral and anti-inflammatory properties. Reported to bind to the cell surface receptor, TLR7 (toll-like receptor 7), and induce the secretion of several pro-inflammatory cytokines and chemokines both in vitro and in vivo.
Form
White solid
Intert gas (Yes/No)
Packaged under inert gas
CAS number
99011-02-6
Chemical formula
C₁₄H₁₆N₄
Structure formula
Purity
≥98% by HPLC
Solubility
DMSO (3 mg/ml); warming to 60°C is required for complete solubilization.
Storage
Protect from light
+2°C to +8°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Upon thawing, warming may be required to resolubilize precipitated product.
Toxicity
Toxic
References
Majewski, S., et al. 2005. Int. J. Dermatol.44, 14. Gibson, S.J., et al. 2002. Cell. Immunol.218, 74. Hemmi, H., et al. 2002. Nat. Immunol.3, 196. Megyeri, K., et al. 1995. Mol. Cell. Biol.15, 2207.
