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401250 Sigma-AldrichIlimaquinone - CAS 71678-03-0 - Calbiochem

A cell-permeable marine sponge metabolite with anti-microbial, anti-HIV, anti-inflammatory, and anti-mitotic properties.

Ilimaquinone - CAS 71678-03-0 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

同义词: 3-[(Decahydro-1β,2β,4aβ-trimethyl-5-methylene-1-napthyl)methyl]-2-hydroxy-5-methoxybenzoquinone, IQ

Primary Target: Induces a complete and reversible breakdown of Golgi membranes into smaller vesicular structures and causes depolymerization of microtubules.

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概述

Replacement Information

重要规格表

CAS #	Empirical Formula
71678-03-0	C₂₂H₃₀O₄

价格及供货情况

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Description
Overview	A cell-permeable marine sponge metabolite with anti-microbial, anti-HIV, anti-inflammatory, and anti-mitotic properties. Induces a complete and reversible breakdown of Golgi membranes into smaller vesicular structures and causes depolymerization of microtubules. Inhibits cellular methylations through its interaction with S-adenosylhomocysteinase. Blocks the cytotoxicity of ricin and diphtheria toxin. Acts as an inhibitor of the RNase H activity of HIV-1.
Catalogue Number	401250
Brand Family	Calbiochem®
Synonyms	3-[(Decahydro-1β,2β,4aβ-trimethyl-5-methylene-1-napthyl)methyl]-2-hydroxy-5-methoxybenzoquinone, IQ

References
References	Radeke, H.S., et al. 1999. Chem. Biol. 6, 639. Radeke, H.S., and Snapper, M.L. 1998. Bioorg. Med. Chem. 6, 1227. Jamora, C., et al. 1997. Cell 91, 617. Nambiar, M.P., and Wu, H.C. 1995. Exp. Cell Res. 219, 671. Loya, S., and Hizi, A. 1993. J. Biol. Chem. 268, 9323. Takizawa, P.A., et al. 1993. Cell 73, 1079. Veit, B., et al. 1993. J. Cell Biol. 122, 1197.

Product Information
CAS number	71678-03-0
ATP Competitive	N
Form	Red solid
Hill Formula	C₂₂H₃₀O₄
Chemical formula	C₂₂H₃₀O₄
Reversible	N
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Primary Target	Induces a complete and reversible breakdown of Golgi membranes into smaller vesicular structures and causes depolymerization of microtubules.
Purity	≥98% by HPLC

Physicochemical Information
Cell permeable	N

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Protect from Light	Protect from light
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 3 months at -70°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
401250-100UGCN	04055977188943

Documentation

Ilimaquinone - CAS 71678-03-0 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

Ilimaquinone - CAS 71678-03-0 - Calbiochem 分析证书

标题	批号
401250	输入批号

参考

参考信息概述
Radeke, H.S., et al. 1999. Chem. Biol. 6, 639. Radeke, H.S., and Snapper, M.L. 1998. Bioorg. Med. Chem. 6, 1227. Jamora, C., et al. 1997. Cell 91, 617. Nambiar, M.P., and Wu, H.C. 1995. Exp. Cell Res. 219, 671. Loya, S., and Hizi, A. 1993. J. Biol. Chem. 268, 9323. Takizawa, P.A., et al. 1993. Cell 73, 1079. Veit, B., et al. 1993. J. Cell Biol. 122, 1197.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	14-July-2008 RFH
Synonyms	3-[(Decahydro-1β,2β,4aβ-trimethyl-5-methylene-1-napthyl)methyl]-2-hydroxy-5-methoxybenzoquinone, IQ
Description	A cell-permeable marine sponge metabolite that induces complete and reversible breakdown of Golgi membranes into smaller vesicular structures, possibly through the activation of heterotrimeric G-proteins. Blocks protein transport at the cis-Golgi and depolymerizes microtubules. Also possesses anti-HIV activity and the ability to inhibit the cytotoxicity of ricin and diphtheria toxin.
Form	Red solid
Intert gas (Yes/No)	Packaged under inert gas
CAS number	71678-03-0
Chemical formula	C₂₂H₃₀O₄
Structure formula
Purity	≥98% by HPLC
Solubility	DMSO (200 mg/ml)
Storage	Protect from light -20°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 3 months at -70°C.
Toxicity	Standard Handling
References	Radeke, H.S., et al. 1999. Chem. Biol. 6, 639. Radeke, H.S., and Snapper, M.L. 1998. Bioorg. Med. Chem. 6, 1227. Jamora, C., et al. 1997. Cell 91, 617. Nambiar, M.P., and Wu, H.C. 1995. Exp. Cell Res. 219, 671. Loya, S., and Hizi, A. 1993. J. Biol. Chem. 268, 9323. Takizawa, P.A., et al. 1993. Cell 73, 1079. Veit, B., et al. 1993. J. Cell Biol. 122, 1197.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Extracellular Matrix, Adhesion and Cytoskeletal Research Tools

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