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407621 Sigma-AldrichIL-2Rα Antagonist - CAS 1217448-66-2 - Calbiochem

The IL-2Rα Antagonist, also referenced under CAS 1217448-66-2, controls the biological activity of IL-2Rα.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

同义词: (R)-N-(2-(1-(Aminoiminomethyl)-3-piperidinyl)-1-oxoethyl)-4-(phenylethynyl)-L-phenylalanine methyl ester, trifluoroacetate, Ro26-4550

Primary Target: Inhibitor of the IL-2/IL-2Rα interaction

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概述

重要规格表

CAS #	Empirical Formula
1217448-66-2	C₂₆H₃₀N₄O₃ • CF₃CO₂H

价格及供货情况

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Description
Overview	A non-peptidyl acylphenylalanine compound that binds to IL-2 and acts as a competitive inhibitor of the IL-2/IL-2Rα interaction (IC₅₀ = 3 µM).
Catalogue Number	407621
Brand Family	Calbiochem®
Synonyms	(R)-N-(2-(1-(Aminoiminomethyl)-3-piperidinyl)-1-oxoethyl)-4-(phenylethynyl)-L-phenylalanine methyl ester, trifluoroacetate, Ro26-4550

References
References	Emerson, S.D., et al. 2003. Protein Science 12, 811. Tilley, J.W., et al. 1997. J. Am. Chem. Soc. 119, 7589.

Product Information
CAS number	1217448-66-2
ATP Competitive	N
Form	White solid
Hill Formula	C₂₆H₃₀N₄O₃ • CF₃CO₂H
Chemical formula	C₂₆H₃₀N₄O₃ • CF₃CO₂H
Hygroscopic	Hygroscopic
Reversible	N
Structure formula Image
Quality Level	MQ100

Biological Information
Primary Target	Inhibitor of the IL-2/IL-2Rα interaction
Primary Target IC<sub>50</sub>	3 µM against IL-2/IL-2Rα interaction
Purity	≥95% by HPLC

Physicochemical Information
Cell permeable	N

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	+2°C to +8°C
Protect from Light	Protect from light
Hygroscopic	Hygroscopic
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Global Trade Item Number
产品目录编号	GTIN
407621-5MGCN	04055977211368

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