Millipore Sigma Vibrant Logo

376817 Hexokinase II Inhibitor II, 3-BP - CAS 1113-59-3 - Calbiochem

The Hexokinase II Inhibitor II, 3-BP, also referenced under CAS 1113-59-3, controls the biological activity of Hexokinase II. This small molecule/inhibitor is primarily used for Cell Structure applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

同义词: 3-BrPA, Bromopyruvate, Bromopyruvatic Acid, 3-Bromo-2-oxopropionic acid

View Products on Sigmaaldrich.com
376817
查看价格及供货情况

概述

Replacement Information

重要规格表

CAS #Empirical Formula
1113-59-3C₃H₃BrO₃

价格及供货情况

产品目录编号 库存情况包装 数量 / 包装 价格 数量
376817-100MGCN
正在查询供货情况......
—
目前缺货 目前缺货
有货 
停产
少量现货
供货情况有待确认
    其余：另行通知
      其余：另行通知
      另行通知
      联系客户服务
      Contact Customer Service

      		 100 mg
      正在检索价格......
      无法检索价格。
      最小订购数量为倍数
      Maximum Quantity is
      以订单确认为准 更多信息
      您节约了 ()。
       
      —
      Request Pricing
      		 —
      Description
      OverviewA cell-permeable pyruvic acid derivative that acts as an inhibitor against hexokinase II-mediated glycolysis and effectively suppress tumor survival both in cultures in vitro and in mice and rats in vivo.
      Catalogue Number376817
      Brand Family Calbiochem®
      Synonyms3-BrPA, Bromopyruvate, Bromopyruvatic Acid, 3-Bromo-2-oxopropionic acid
      References
      ReferencesBujis, M., et al. 2009. Invest. New Drugs 27, 120.
      Chen, Z., et al. 2009. Biochim. Biophys. Acta. 1787, 553.
      Hulleman, E., et al. 2009. Blood. 113, 2014;
      Mathupala, S.P., et al. 2009. Semin. Cancer Biol. 19, 17.
      Pereira da Silva, A.P., et al. 2009. Biochem. J. 417, 717.
      Yun, J., et al. 2009. Science. 325, 1555.
      Zhang, X., et al. 2009. Anticancer Res. 29, 1443.
      Kim, J.S., et al. 2008. J. Bioenerg. Biomembr. 40, 607.
      Product Information
      CAS number1113-59-3
      EC number214-206-5
      FormWhite crystalline solid
      Hill FormulaC₃H₃BrO₃
      Chemical formulaC₃H₃BrO₃
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥97% by Titration
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSUZ0840000
      Safety Information
      R PhraseR: 34

      Causes burns.
      S PhraseS: 26-36/37/39-45

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing, gloves and eye/face protection.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Corrosive
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      产品目录编号 GTIN
      376817-100MGCN 04055977212983

      Documentation

      Hexokinase II Inhibitor II, 3-BP - CAS 1113-59-3 - Calbiochem MSDS

      职位

      物料安全数据表 (MSDS) 

      Hexokinase II Inhibitor II, 3-BP - CAS 1113-59-3 - Calbiochem 分析证书

      标题批号
      376817

      参考

      参考信息概述
      Bujis, M., et al. 2009. Invest. New Drugs 27, 120.
      Chen, Z., et al. 2009. Biochim. Biophys. Acta. 1787, 553.
      Hulleman, E., et al. 2009. Blood. 113, 2014;
      Mathupala, S.P., et al. 2009. Semin. Cancer Biol. 19, 17.
      Pereira da Silva, A.P., et al. 2009. Biochem. J. 417, 717.
      Yun, J., et al. 2009. Science. 325, 1555.
      Zhang, X., et al. 2009. Anticancer Res. 29, 1443.
      Kim, J.S., et al. 2008. J. Bioenerg. Biomembr. 40, 607.
      数据表

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision02-December-2010 RFH
      Synonyms3-BrPA, Bromopyruvate, Bromopyruvatic Acid, 3-Bromo-2-oxopropionic acid
      DescriptionA cell-permeable pyruvic acid derivative that acts as an inhibitor against hexokinase II-mediated glycolysis and effectively suppress tumor survival both in cultures in vitro and in mice and rats in vivo.
      FormWhite crystalline solid
      CAS number1113-59-3
      RTECSUZ0840000
      EC number214-206-5
      Chemical formulaC₃H₃BrO₃
      Structure formulaStructure formula
      Purity≥97% by Titration
      SolubilityDMSO (100 mg/ml) or dH₂O (100 mg/ml)
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Corrosive
      ReferencesBujis, M., et al. 2009. Invest. New Drugs 27, 120.
      Chen, Z., et al. 2009. Biochim. Biophys. Acta. 1787, 553.
      Hulleman, E., et al. 2009. Blood. 113, 2014;
      Mathupala, S.P., et al. 2009. Semin. Cancer Biol. 19, 17.
      Pereira da Silva, A.P., et al. 2009. Biochem. J. 417, 717.
      Yun, J., et al. 2009. Science. 325, 1555.
      Zhang, X., et al. 2009. Anticancer Res. 29, 1443.
      Kim, J.S., et al. 2008. J. Bioenerg. Biomembr. 40, 607.