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373402 Sigma-AldrichHedgehog Antagonist VIII - CAS 330796-24-2 - Calbiochem

The Hedgehog Antagonist VIII, also referenced under CAS 330796-24-2, controls the biological activity of Hedgehog. This small molecule/inhibitor is primarily used for Cell Signaling applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

同义词: 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-((3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl)methyl)-urea, Hh Signaling Antagonist VIII

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概述

Replacement Information

重要规格表

CAS #	Empirical Formula
330796-24-2	C₂₃H₁₅ClF₄N₄O₂

价格及供货情况

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Description
Overview	A cell-permeable quinazolinyl-urea compound that is shown to potently inhibit OCT-Shh-stimulated Gli transcription activity in a 10t1/2(s12) cell-based Luciferase reporter assay (IC₅₀ = 70 nM).
Catalogue Number	373402
Brand Family	Calbiochem®
Synonyms	1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-((3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl)methyl)-urea, Hh Signaling Antagonist VIII

References
References	Brunton, A.A., et al. 2008. J. Med. Chem. 51, 1108.

Product Information
CAS number	330796-24-2
Form	Clear slightly yellow solid
Hill Formula	C₂₃H₁₅ClF₄N₄O₂
Chemical formula	C₂₃H₁₅ClF₄N₄O₂
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Purity	≥95% by HPLC

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	+2°C to +8°C
Protect from Light	Protect from light
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C0. Stock solutions are stable for up to 3 months at -20°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
373402-5MGCN	04055977191127

Documentation

Hedgehog Antagonist VIII - CAS 330796-24-2 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

Hedgehog Antagonist VIII - CAS 330796-24-2 - Calbiochem 分析证书

标题	批号
373402	输入批号

参考

参考信息概述
Brunton, A.A., et al. 2008. J. Med. Chem. 51, 1108.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	23-December-2009 RFH
Synonyms	1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-((3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl)methyl)-urea, Hh Signaling Antagonist VIII
Description	A cell-permeable quinazolinyl-urea compound that is shown to potently inhibit OCT-Shh-stimulated Gli transcription activity in a 10t1/2(s12) cell-based Luciferase reporter assay (IC₅₀ = 70 nM).
Form	Clear slightly yellow solid
Intert gas (Yes/No)	Packaged under inert gas
CAS number	330796-24-2
Chemical formula	C₂₃H₁₅ClF₄N₄O₂
Structure formula
Purity	≥95% by HPLC
Solubility	DMSO (100 mg/ml)
Storage	Protect from light +2°C to +8°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C0. Stock solutions are stable for up to 3 months at -20°C.
Toxicity	Standard Handling
References	Brunton, A.A., et al. 2008. J. Med. Chem. 51, 1108.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Stem Cell Biology > Sonic Hedgehog Signaling Inhibitors

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