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361515 Sigma-AldrichGlycogen Phosphorylase Inhibitor - CAS 648926-15-2 - Calbiochem

The Glycogen Phosphorylase Inhibitor, also referenced under CAS 648926-15-2, controls the biological activity of Glycogen Phosphorylase.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

同义词: 1-(3-(3-(2-Chloro-4,5-difluorobenzoyl)ureido)-4-methoxyphenyl)-3-methylurea

Primary Target: Glycogen phosphorylase

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概述

Replacement Information

重要规格表

CAS #	Empirical Formula
648926-15-2	C₁₇H₁₅ClF₂N₄O₄

价格及供货情况

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361515-1MGCN	正在查询供货情况...... — 目前缺货有货停产少量现货供货情况有待确认登录查看库存有货目前缺货有货其余：另行通知其余：另行通知另行通知联系客户服务 Contact Customer Service 联系客户服务联系客户服务	塑胶安瓿;塑胶针药瓶	1 mg	正在检索价格...... 无法检索价格。最小订购数量为倍数 Maximum Quantity is 以订单确认为准更多信息您节约了 ()。 — Request Pricing 登录查看价格	查看库存情况 —	添加到收藏夹添加到收藏夹添加到我的收藏夹
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Description
Overview	A cell-permeable urea compound that acts as a potent and AMP-competitive inhibitor of glycogen phosphorylase (GP; IC₅₀ = 53 nM). Shown to inhibit glucagon-induced glyocgenolysis both in hepatocytes (IC₅₀ = 380 nM) in vitro and in rats (5 mg/kg, iv) in vivo.
Catalogue Number	361515
Brand Family	Calbiochem®
Synonyms	1-(3-(3-(2-Chloro-4,5-difluorobenzoyl)ureido)-4-methoxyphenyl)-3-methylurea

References
References	Klabunde, T., et al. 2005. J. Med. Chem. 48, 6178

Product Information
CAS number	648926-15-2
ATP Competitive	N
Form	White solid
Hill Formula	C₁₇H₁₅ClF₂N₄O₄
Chemical formula	C₁₇H₁₅ClF₂N₄O₄
Reversible	N
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Primary Target	Glycogen phosphorylase
Primary Target IC<sub>50</sub>	53 nM against glycogen phosphorylase
Purity	≥98% by HPLC

Physicochemical Information
Cell permeable	Y

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Irritant
Storage	+2°C to +8°C
Protect from Light	Protect from light
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
361515-1MGCN	04055977192902
361515-5MGCN	04055977192919

Documentation

Glycogen Phosphorylase Inhibitor - CAS 648926-15-2 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

Glycogen Phosphorylase Inhibitor - CAS 648926-15-2 - Calbiochem 分析证书

标题	批号
361515	输入批号

参考

参考信息概述
Klabunde, T., et al. 2005. J. Med. Chem. 48, 6178

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	01-July-2008 RFH
Synonyms	1-(3-(3-(2-Chloro-4,5-difluorobenzoyl)ureido)-4-methoxyphenyl)-3-methylurea
Description	A cell-permeable urea compound that acts as a potent and AMP-competitive inhibitor of glycogen phosphorylase (GP; IC₅₀ = 53 nM). Shown to inhibit glucagon-induced glyocgenolysis both in hepatocytes (IC₅₀ = 380 nM) in vitro and in rats (5 mg/kg, iv) in vivo.
Form	White solid
Intert gas (Yes/No)	Packaged under inert gas
CAS number	648926-15-2
Chemical formula	C₁₇H₁₅ClF₂N₄O₄
Structure formula
Purity	≥98% by HPLC
Solubility	DMSO (25 mg/ml)
Storage	Protect from light +2°C to +8°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity	Irritant
References	Klabunde, T., et al. 2005. J. Med. Chem. 48, 6178

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Other Inhibitors of Biological Interest > Glycoprotein Processing and Trafficking Inhibitors

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