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			96-Well Plate

数量	产品目录编号	订购说明	数量 / 包装	公开价
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

345733 Sigma-AldrichGanglioside GM₃, Monosialo, Ammonium Salt, Bovine Milk - Calbiochem

Contains mainly N-acetylneuraminic acid.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
小册子
Data Sheet

同义词: Neu5Acα2,3Galβ1,4Glcβ1,1 Ceramide, NH₄

Recommended Products

概述

Replacement Information

重要规格表

Empirical Formula
C₆₄H₁₁₈N₂O₂₁ · NH₄

价格及供货情况

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Description
Overview	Contains mainly N-acetylneuraminic acid. GM₃ and its derivatives play important roles in immunoregulation and in biosynthesis and metabolism of higher gangliosides. GM₃ is reported to inhibit EGF-receptor tyrosine kinase activity in whole cells and plasma membranes, and in detergent micelles. Inhibits protein kinase C activity in both cytosolic and total particulate fractions (IC₅₀ = 100 - 115 µM). Induces the down-modulation of CD4 molecules. Useful as a substrate for neuraminidases. Binds EGF and FGF.
Overview	M.W. 1198.5 (based on stearoyl - 18:0).
Catalogue Number	345733
Brand Family	Calbiochem®
Synonyms	Neu5Acα2,3Galβ1,4Glcβ1,1 Ceramide, NH₄

References
References	Katoh, N. 1995. Life Sci. 56, 157. Sorice, M., et al. 1995. Scand. J. Immunol. 41, 148. Kadowaki, H., and Grant, M.A. 1994. J. Biol. Chem. 269, 14931. Muthing, J., et al. 1994. J. Biochem. (Tokyo) 116, 64.

Product Information
ATP Competitive	N
Form	White solid
Hill Formula	C₆₄H₁₁₈N₂O₂₁ · NH₄
Chemical formula	C₆₄H₁₁₈N₂O₂₁ · NH₄
Reversible	N
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Primary Target	Protein kinase C, EGF-receptor tyrosine kinase
Primary Target IC<sub>50</sub>	100 - 115 µM inhibiting protein kinase C activity in both cytosolic and total particulate fractions
Purity	≥98% by TLC

Physicochemical Information
Cell permeable	N

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information
R Phrase	R: 36/37/38 Irritating to eyes, respiratory system and skin.
S Phrase	S: 26-36 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing.

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Irritant
Storage	-20°C
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
345733-500UGCN	04055977193824

Documentation

Ganglioside GM₃, Monosialo, Ammonium Salt, Bovine Milk - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

Ganglioside GM₃, Monosialo, Ammonium Salt, Bovine Milk - Calbiochem 分析证书

标题	批号
345733	输入批号

参考

参考信息概述
Katoh, N. 1995. Life Sci. 56, 157. Sorice, M., et al. 1995. Scand. J. Immunol. 41, 148. Kadowaki, H., and Grant, M.A. 1994. J. Biol. Chem. 269, 14931. Muthing, J., et al. 1994. J. Biochem. (Tokyo) 116, 64.

小册子

标题
Gangliosides Technical Bulletin

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	13-September-2007 RFH
Synonyms	Neu5Acα2,3Galβ1,4Glcβ1,1 Ceramide, NH₄
Description	Contains mainly N-acetylneuraminic acid. GM₃ and its derivatives play important roles in immunoregulation and in the biosynthesis and metabolism of higher gangliosides. Inhibits protein kinase C activity in both cytosolic and total particulate fractions(IC₅₀ = 100-115 µM). Induces the down-modulation of CD4 molecules. Useful as a substrate for neuraminidases. Binds EGF and FGF.
Form	White solid
Chemical formula	C₆₄H₁₁₈N₂O₂₁ · NH₄
Structure formula
Purity	≥98% by TLC
Solubility	Chloroform:Methanol (2:1)
Storage	-20°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity	Irritant
References	Katoh, N. 1995. Life Sci. 56, 157. Sorice, M., et al. 1995. Scand. J. Immunol. 41, 148. Kadowaki, H., and Grant, M.A. 1994. J. Biol. Chem. 269, 14931. Muthing, J., et al. 1994. J. Biochem. (Tokyo) 116, 64.

种类

Life Science Research > Inhibitors and Biochemicals > Biochemicals > Lipids > Gangliosides

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