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Fibrinogen, CAS 9001-32-5 , is a soluble plasma glycoprotein that is synthesized in the hepatic parenchymal cells. Contains >90% clottable protein.
More>>Fibrinogen, CAS 9001-32-5 , is a soluble plasma glycoprotein that is synthesized in the hepatic parenchymal cells. Contains >90% clottable protein. Less<<
Fibrinogen, Human Plasma MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Native fibrinogen from human plasma. A plasma glycoprotein, essential for clotting of blood, synthesized and secreted by hepatic parenchymal cells. Contains ≥ 90% clottable proteins.
Do not disturb until the fibrinogen is completely solubilized.
Catalogue Number
341576
Brand Family
Calbiochem®
Synonyms
Coagulation Factor I
References
Product Information
CAS number
9001-32-5
Form
Lyophilized
Formulation
Lyophilized from 20 mM sodium citrate-HCl, pH 7.4.
Fibrinogen, CAS 9001-32-5 , is a soluble plasma glycoprotein that is synthesized in the hepatic parenchymal cells. Contains >90% clottable protein.
Biological Information
Biological activity
Contains ≥90% clottable proteins.
Purity
homogeneous by SDS-PAGE.
Source
Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R Phrase
R: 20/21/22
Harmful by inhalation, in contact with skin and if swallowed.
S Phrase
S: 36
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code
Ambient Temperature Only
Toxicity
Harmful
Storage
+2°C to +8°C
Do not freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-70°C). Do not store solutions on ice; precipitation will occur. Stock solutions are stable for up to 6 months at -70°C. Avoid freeze-thaw cycles.
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
27-September-2007 RFH
Synonyms
Coagulation Factor I
Description
Native fibrinogen from human plasma. A plasma glycoprotein, essential for clotting blood. Synthesized and secreted by hepatic parenchymal cells. Fibrinogen, also known as Coagulation Factor I, is an acute-phase plasma protein found at a concentration of about 300 mg/100 ml. Conversion of soluble fibrinogen to the insoluble clot-forming fibrin is the terminal stage of blood clotting. Clinically, fibrinogen is found at elevated levels during pregnancy, after surgical trauma, or in cases of myocardial infarction, and is decreased in cases of liver cirrhosis and serum hepatitis.
Form
Lyophilized
Formulation
Lyophilized from 20 mM sodium citrate-HCl, pH 7.4.
Source
Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
CAS number
9001-32-5
Purity
homogeneous by SDS-PAGE.
Biological activity
Contains ≥90% clottable proteins.
Solubility
Sterile distilled H₂O. Protein must be thawed in a 37°C water bath. Solutions used to reconstitute fibrinogen should first be brought to 37°C. Once at 37°C, the solution can be added to the fibrinogen and this mixture should remain at 37°C until the fibrinogen is completely solubilized. If the vial is disturbed before the fibrinogen is completely dissolved, the fibrinogen will precipitate. Please see vial label for lot-specific reconstitution volume.
Storage
+2°C to +8°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-70°C). Do not store solutions on ice; precipitation will occur. Stock solutions are stable for up to 6 months at -70°C. Avoid freeze-thaw cycles.
