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344145 FPTase, Rat, Recombinant, E. coli

FPTase, Rat, Recombinant, E. coli, a heterodimeric enzyme catalyzes the transfer of a 15-carbon isoprenoid group to a variety of cellular proteins. Recognizes the C-terminal CAAX cysteine motif.

FPTase, Rat, Recombinant, E. coli MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

同义词: Farnesyl Proteintransferase, FTase

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344145
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概述

Replacement Information

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344145-100UGCN
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      		 塑胶安瓿;塑胶针药瓶 100 μg
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      Description
      OverviewRecombinant, rat FPTase expressed in E. coli. A heterodimeric enzyme that catalyzes the transfer of a 15-carbon isoprenoid group to a variety of cellular proteins including Ras. Recognizes the C-terminal CAAX cysteine motif where the farnesylated cysteine is followed by two aliphatic amino acids and either leucine or serine.
      M.W. α-subunit: ~48,000; β-subunit: ~46,000
      Catalogue Number344145
      Brand Family Calbiochem®
      SynonymsFarnesyl Proteintransferase, FTase
      References
      ReferencesHightower, K.E., et al. 2001. Biochem. J. 360, 625.
      Zimmerman, K.K., et al. 1998. Protein Expr. Purif. 14, 395.
      Reiss, Y., et al. 1990. Cell 62, 81.
      Product Information
      FormLiquid
      FormulationIn 25 mM HEPES, pH 7.2, 40 mM NaCl, 5 µM ZnCl₂, 1 mM TECP
      Quality LevelMQ200
      Applications
      ApplicationFPTase, Rat, Recombinant, E. coli, a heterodimeric enzyme catalyzes the transfer of a 15-carbon isoprenoid group to a variety of cellular proteins. Recognizes the C-terminal CAAX cysteine motif.
      Biological Information
      Biological activity1 pmol of FPTase will transfer 1 pmol of farnesyl to H-Ras in 15 min at 37°C.
      Purity≥85% by SDS-PAGE
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      产品目录编号 GTIN
      344145-100UGCN 04055977215229

      Documentation

      FPTase, Rat, Recombinant, E. coli MSDS

      职位

      物料安全数据表 (MSDS) 

      FPTase, Rat, Recombinant, E. coli 分析证书

      标题批号
      344145

      参考

      参考信息概述
      Hightower, K.E., et al. 2001. Biochem. J. 360, 625.
      Zimmerman, K.K., et al. 1998. Protein Expr. Purif. 14, 395.
      Reiss, Y., et al. 1990. Cell 62, 81.
      数据表

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision30-March-2023 JSW
      SynonymsFarnesyl Proteintransferase, FTase
      DescriptionRecombinant, rat FPTase expressed in E. coli. A heterodimeric enzyme that catalyzes the transfer of a 15-carbon isoprenoid group to a C-terminal cysteine in a variety of cellular proteins, including Ras. Recognizes the CaaX motif where the farnesylated cysteine (C) is followed by two aliphatic amino acids (aa) and either leucine or serine (X). Expressed in E. coli as an untagged recombinant protein.
      FormLiquid
      FormulationIn 25 mM HEPES, pH 7.2, 40 mM NaCl, 5 µM ZnCl₂, 1 mM TECP
      Purity≥85% by SDS-PAGE
      Biological activity1 pmol of FPTase will transfer 1 pmol of farnesyl to H-Ras in 15 min at 37°C.
      Storage Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Toxicity Standard Handling
      ReferencesHightower, K.E., et al. 2001. Biochem. J. 360, 625.
      Zimmerman, K.K., et al. 1998. Protein Expr. Purif. 14, 395.
      Reiss, Y., et al. 1990. Cell 62, 81.