数量	产品目录编号	订购说明	数量 / 包装	公开价
			96-Well Plate

数量	产品目录编号	订购说明	数量 / 包装	公开价
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

344152 Sigma-AldrichFPT Inhibitor II - Calbiochem

The FPT Inhibitor II controls the biological activity of FPT. This small molecule/inhibitor is primarily used for Cancer applications.

FPT Inhibitor II - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

同义词: (E,E)-2-[2-Oxo-2-[[(3,7,11-trimethyl-2,6,10-dodecatrienyl)oxy]amino]ethyl]phosphonic Acid, 2Na

Primary Target: Farnesyltransferase (Ftase)

View Products on Sigmaaldrich.com

Recommended Products

概述

Replacement Information

重要规格表

Empirical Formula
C₁₇H₂₈NO₅P • 2Na

价格及供货情况

产品目录编号	库存情况	包装	数量 / 包装	价格	数量
344152-1MGCN	正在查询供货情况...... — 目前缺货有货停产少量现货供货情况有待确认登录查看库存有货目前缺货有货其余：另行通知其余：另行通知另行通知联系客户服务 Contact Customer Service 联系客户服务联系客户服务	塑胶安瓿;塑胶针药瓶	1 mg	正在检索价格...... 无法检索价格。最小订购数量为倍数 Maximum Quantity is 以订单确认为准更多信息您节约了 ()。 — Request Pricing 登录查看价格	查看库存情况 —	添加到收藏夹添加到收藏夹添加到我的收藏夹

Description
Overview	A cell permeable potent and selective inhibitor of farnesyltransferase (FTase; IC₅₀ = 75 nM). Also inhibits Ras farnesylation in whole cells by ~90% at 25-250 µM. Resistant to cleavage by phosphorylation. Please note that the molecular weight for this compound is batch-specific due to variable water content. Please refer to the vial label or the certificate of analysis for the batch-specific molecular weight. The molecular weight provided represents the baseline molecular weight without water.
Catalogue Number	344152
Brand Family	Calbiochem®
Synonyms	(E,E)-2-[2-Oxo-2-[[(3,7,11-trimethyl-2,6,10-dodecatrienyl)oxy]amino]ethyl]phosphonic Acid, 2Na

References
References	Manne, V., et al. 1995. Drug Development Res. 34, 121.

Product Information
ATP Competitive	N
Form	White solid
Hill Formula	C₁₇H₂₈NO₅P • 2Na
Chemical formula	C₁₇H₂₈NO₅P • 2Na
Hygroscopic	Hygroscopic
Reversible	N
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Primary Target	Farnesyltransferase (Ftase)
Primary Target IC<sub>50</sub>	75 nM against Ftase
Purity	≥95% by HPLC

Physicochemical Information
Cell permeable	Y

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Hygroscopic	Hygroscopic
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
344152-1MGCN	04055977215267

Documentation

FPT Inhibitor II - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

FPT Inhibitor II - Calbiochem 分析证书

标题	批号
344152	输入批号

参考

参考信息概述
Manne, V., et al. 1995. Drug Development Res. 34, 121.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	23-March-2018 JSW
Synonyms	(E,E)-2-[2-Oxo-2-[[(3,7,11-trimethyl-2,6,10-dodecatrienyl)oxy]amino]ethyl]phosphonic Acid, 2Na
Description	A highly selective and potent inhibitor of Ras farnesyltransferase (IC₅₀ = 75 nM). Inhibits geranylgeranyltransferase I (IC₅₀ = 24 µM) and II (IC₅₀ = 24 µM) at much higher concentrations. Also inhibits Ras farnesylation in whole cells by ~90% at 10-100 µg/ml (25-250 µM). Resistant to cleavage by phosphorylation.
Form	White solid
Chemical formula	C₁₇H₂₈NO₅P • 2Na
Structure formula
Purity	≥95% by HPLC
Solubility	H₂O (≥10 mg/ml)
Storage	-20°C Hygroscopic
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
Toxicity	Standard Handling
References	Manne, V., et al. 1995. Drug Development Res. 34, 121.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Other Inhibitors of Biological Interest > Farnesyltransferase (FTase), Geranylgeranyltransferase (GGTase), & Methyltransferase Inhibitors

此产品已添加到您的购物车。