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			96-Well Plate

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	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

05-23-3801 Sigma-AldrichEndothelin 3, Human and Rat - CAS 117399-93-6 - Calbiochem

Attenuates thrombin-evoked aggregation of human platelets.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

同义词: ET-3, CTCFTYKDKECVYYCHLDIIW

Primary Target: Stimulator of interleukin-6 production by endothelial cell lines

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概述

Replacement Information

重要规格表

CAS #	Empirical Formula
117399-93-6	C₁₂₁H₁₆₈N₂₆O₃₃S₄

价格及供货情况

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Description
Overview	Attenuates thrombin-evoked aggregation of human platelets. A potent stimulator of interleukin-6 production by endothelial cell lines. Reported to activate phospholipase C in fibroblasts expressing ET_A receptors.
Catalogue Number	05-23-3801
Brand Family	Calbiochem®
Synonyms	ET-3, CTCFTYKDKECVYYCHLDIIW

References
References	Gresser, O., et al. 1996. Biochem. Biophys. Res. Commun. 224, 169. Astarie-Dequeker, C., et al. 1995. Br. J. Pharmacol. 114, 524. Xin, X., et al. 1995. Endocrinology 136, 132. Brunner, F., et al. 1992. J. Mol. Cell. Cardiol. 24, 1291. Lamers, J.M., et al. 1992. Mol. Cell. Biochem. 116, 59.

Product Information
CAS number	117399-93-6
ATP Competitive	N
Form	Solid
Formulation	Supplied as a trifluoroacetate salt. Sold on the basis of peptide content.
Hill Formula	C₁₂₁H₁₆₈N₂₆O₃₃S₄
Chemical formula	C₁₂₁H₁₆₈N₂₆O₃₃S₄
Reversible	N
Sold on the basis of peptide content	Y
Quality Level	MQ100

Applications

Biological Information
Primary Target	Stimulator of interleukin-6 production by endothelial cell lines
Purity	≥97% by HPLC

Physicochemical Information
Cell permeable	N
Peptide Content	Y
Peptide Sequence	H-Cys¹-Thr-Cys³-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys¹¹-Val-Tyr-Tyr-Cys¹⁵-His-Leu-Asp-Ile-Ile-Trp-OH (disulfide bonds: 1 → 15; 3 → 11)

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Storage	-20°C
Protect from Moisture	Protect from moisture
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
05-23-3801-0.5MGCN	04055977226805

Documentation

Endothelin 3, Human and Rat - CAS 117399-93-6 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

Endothelin 3, Human and Rat - CAS 117399-93-6 - Calbiochem 分析证书

标题	批号
05-23-3801	输入批号

参考

参考信息概述
Gresser, O., et al. 1996. Biochem. Biophys. Res. Commun. 224, 169. Astarie-Dequeker, C., et al. 1995. Br. J. Pharmacol. 114, 524. Xin, X., et al. 1995. Endocrinology 136, 132. Brunner, F., et al. 1992. J. Mol. Cell. Cardiol. 24, 1291. Lamers, J.M., et al. 1992. Mol. Cell. Biochem. 116, 59.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	18-September-2008 RFH
Synonyms	ET-3, CTCFTYKDKECVYYCHLDIIW
Description	Attenuates thrombin-evoked aggregation of human platelets. A potent stimulator of interleukin-6 production by endothelial cell lines. Reported to activate phopholipase C in fibroblasts expressing ET_A receptors.
Form	Solid
Formulation	Supplied as a trifluoroacetate salt. Sold on the basis of peptide content.
CAS number	117399-93-6
Chemical formula	C₁₂₁H₁₆₈N₂₆O₃₃S₄
Peptide Sequence	H-Cys¹-Thr-Cys³-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys¹¹-Val-Tyr-Tyr-Cys¹⁵-His-Leu-Asp-Ile-Ile-Trp-OH (disulfide bonds: 1 → 15; 3 → 11)
Purity	≥97% by HPLC
Solubility	5% Acetic acid (0.5 mg/ml). Dissolve peptide initially at 8 mg/ml in 80% cold acetic acid, then dilute with cold water to 5% acetic acid and 0.5 mg/ml peptide.
Storage	Protect from moisture -20°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
References	Gresser, O., et al. 1996. Biochem. Biophys. Res. Commun. 224, 169. Astarie-Dequeker, C., et al. 1995. Br. J. Pharmacol. 114, 524. Xin, X., et al. 1995. Endocrinology 136, 132. Brunner, F., et al. 1992. J. Mol. Cell. Cardiol. 24, 1291. Lamers, J.M., et al. 1992. Mol. Cell. Biochem. 116, 59.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Neurochemicals > Agonists > Endothelin Receptor Agonists

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