数量	产品目录编号	订购说明	数量 / 包装	公开价
			96-Well Plate

数量	产品目录编号	订购说明	数量 / 包装	公开价
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

324483 Sigma-AldrichEbselen - CAS 60940-34-3 - Calbiochem

A cell-permeable, non-selective inhibitor of COX-1 and COX-2.

Ebselen - CAS 60940-34-3 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
小册子
Data Sheet

同义词: 2-Phenyl-1,2-benzisoselenazol-3(2H)-one, PZ51

Primary Target: COX-1, COX-2

Recommended Products

概述

Replacement Information

重要规格表

CAS #	Empirical Formula
60940-34-3	C₁₃H₉NOSe

价格及供货情况

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Description
Overview	A cell-permeable, non-selective inhibitor of COX-1 and COX-2. An excellent scavenger of peroxynitrite. Glutathione peroxidase mimetic. Inhibits radiation-induced apoptosis in thymocytes by scavenging peroxides. A neuroprotective agent active against acute focal ischemic injury. Inhibits LPS-induced NF-κB nuclear translocation and LPS-induced phosphorylation of JNK.
Catalogue Number	324483
Brand Family	Calbiochem®
Synonyms	2-Phenyl-1,2-benzisoselenazol-3(2H)-one, PZ51

References
References	Shimohashi, N., et al. 2000. J. Cell Biochem. 78, 595. Ramakrishnan, N., et al. 1996. Biochem. Pharmacol. 51, 1443. Ullrich, V., et al. 1996. Biochem. Pharmacol. 52, 15. Dawson, D.A., et al. 1995. Neurosci. Lett. 185, 65. Wang, J.F., et al. 1992. Hepatology 5, 112. Maiorino, M., et al. 1988. Biochem. Pharmacol. 37, 2267. Parnham, M.J., and Graf, E. 1987. Biochem. Pharmacol. 36, 3095. Parnham, M.J., and Kindt, S. 1984. Biochem. Pharmacol. 33, 3247.

References

Shimohashi, N., et al. 2000. J. Cell Biochem. 78, 595.
Ramakrishnan, N., et al. 1996. Biochem. Pharmacol. 51, 1443.
Ullrich, V., et al. 1996. Biochem. Pharmacol. 52, 15.
Dawson, D.A., et al. 1995. Neurosci. Lett. 185, 65.
Wang, J.F., et al. 1992. Hepatology 5, 112.
Maiorino, M., et al. 1988. Biochem. Pharmacol. 37, 2267.
Parnham, M.J., and Graf, E. 1987. Biochem. Pharmacol. 36, 3095.
Parnham, M.J., and Kindt, S. 1984. Biochem. Pharmacol. 33, 3247.

Product Information
CAS number	60940-34-3
ATP Competitive	N
Form	Lyophilized solid
Hill Formula	C₁₃H₉NOSe
Chemical formula	C₁₃H₉NOSe
Reversible	N
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Primary Target	COX-1, COX-2
Purity	≥98% by TLC

Physicochemical Information
Cell permeable	Y

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Do not freeze	Ok to freeze
Special Instructions	Following reconstituion, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
324483-5MGCN	04055977197242

Documentation

Ebselen - CAS 60940-34-3 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

Ebselen - CAS 60940-34-3 - Calbiochem 分析证书

标题	批号
324483	输入批号

参考

参考信息概述
Shimohashi, N., et al. 2000. J. Cell Biochem. 78, 595. Ramakrishnan, N., et al. 1996. Biochem. Pharmacol. 51, 1443. Ullrich, V., et al. 1996. Biochem. Pharmacol. 52, 15. Dawson, D.A., et al. 1995. Neurosci. Lett. 185, 65. Wang, J.F., et al. 1992. Hepatology 5, 112. Maiorino, M., et al. 1988. Biochem. Pharmacol. 37, 2267. Parnham, M.J., and Graf, E. 1987. Biochem. Pharmacol. 36, 3095. Parnham, M.J., and Kindt, S. 1984. Biochem. Pharmacol. 33, 3247.

参考信息概述

小册子

标题
Alzheimer's Disease Brochure & Technical Guide

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	19-June-2008 RFH
Synonyms	2-Phenyl-1,2-benzisoselenazol-3(2H)-one, PZ51
Description	Non-selective, cell-permeable, inhibitor of the cyclooxygenase activity of prostaglandin H synthase 1 and 2. An excellent scavenger of peroxynitrite. Glutathione peroxidase mimetic. Inhibits radiation-induced apoptosis in thymocytes by scavenging peroxides. A neuroprotective agent against acute focal ischemic injury.
Form	Lyophilized solid
CAS number	60940-34-3
Chemical formula	C₁₃H₉NOSe
Structure formula
Purity	≥98% by TLC
Solubility	DMSO (5 mg/ml) or Ethanol
Storage	-20°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstituion, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity	Standard Handling
References	Shimohashi, N., et al. 2000. J. Cell Biochem. 78, 595. Ramakrishnan, N., et al. 1996. Biochem. Pharmacol. 51, 1443. Ullrich, V., et al. 1996. Biochem. Pharmacol. 52, 15. Dawson, D.A., et al. 1995. Neurosci. Lett. 185, 65. Wang, J.F., et al. 1992. Hepatology 5, 112. Maiorino, M., et al. 1988. Biochem. Pharmacol. 37, 2267. Parnham, M.J., and Graf, E. 1987. Biochem. Pharmacol. 36, 3095. Parnham, M.J., and Kindt, S. 1984. Biochem. Pharmacol. 33, 3247.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Lipid Signaling Inhibitors > Cyclooxygenase (COX) Inhibitors

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