数量	产品目录编号	订购说明	数量 / 包装	公开价
			96-Well Plate

数量	产品目录编号	订购说明	数量 / 包装	公开价
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

324674 Sigma-AldrichEGFR Inhibitor - CAS 879127-07-8 - Calbiochem

The EGFR Inhibitor, also referenced under CAS 879127-07-8, controls the biological activity of EGFR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applica

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MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Primary Target: EGFR

412510 Sigma-Aldrich
IRE1 Inhibitor I, STF-083010 - Calbiochem
OP92 Sigma-Aldrich
Anti-BRCA1 (Ab-1) Mouse mAb (MS110)
1088830500 Supelco
七水合硫酸锌
574795-1L Millipore
TBE Buffer, 10X, Molecular Biology Grade - Calbiochem
07-091 Sigma-Aldrich
Anti-Pin1 Antibody
HCYTA-60K Millipore
MILLIPLEX^® Human Cytokine/Chemokine/Growth Factor Panel A - Immunology Multiplex Assay
509612 Sigma-Aldrich
InSolution™ TAPI-2 - CAS 187034-31-7 - Calbiochem
P3C010C01 Millipore
Pellicon® 3 Cassette with Ultracel® 10 kDa Membrane, C screen, 0.11 m²

CAS #	Empirical Formula
879127-07-8	C₂₁H₁₈F₃N₅O

产品目录编号	库存情况	包装	数量 / 包装	价格	数量
324674-1MGCN	正在查询供货情况...... — 目前缺货有货停产少量现货供货情况有待确认登录查看库存有货目前缺货有货其余：另行通知其余：另行通知另行通知联系客户服务 Contact Customer Service 联系客户服务联系客户服务	塑胶安瓿;塑胶针药瓶	1 mg	正在检索价格...... 无法检索价格。最小订购数量为倍数 Maximum Quantity is 以订单确认为准更多信息您节约了 ()。 — Request Pricing 登录查看价格	查看库存情况 —	添加到收藏夹添加到收藏夹添加到我的收藏夹

Description
Overview	A cell-permeable 4,6-dianilinopyrimidine compound that acts as a potent, ATP-competitive, and highly selective inhibitor of EGFR and some EGFR mutants (IC₅₀ = 21 nM, 63 nM, and 4 nM for EGFRwt, EGFR^L858R and EGFR^L861Q, respectively) vs. erbB4/Her4 (IC₅₀ = 7.64 µM) and a panel of 55 other kinases. Shown to completely block EGF-induced EGFR autophosphorylation in U-2OS cells at 10 µM.
Catalogue Number	324674
Brand Family	Calbiochem®
Synonyms	Cyclopropanecarboxylic acid-(3-(6-(3-trifluoromethyl-phenylamino)-pyrimidin-4-ylamino)-phenyl)-amide

References
References	Zhang, Q., et al. 2006. J. Am. Chem. Soc. 128, 2182

Biological Information
Primary Target	EGFR
Primary Target IC<sub>50</sub>	21 nM, 63 nM, and 4 nM for EGFRwt, EGFRL858R and EGFRL861Q, respectively
Purity	≥97% by HPLC

Physicochemical Information
Cell permeable	Y

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Protect from Light	Protect from light
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Global Trade Item Number
产品目录编号	GTIN
324674-1MGCN	04055977196764

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