数量	产品目录编号	订购说明	数量 / 包装	公开价
			96-Well Plate

数量	产品目录编号	订购说明	数量 / 包装	公开价
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

317642 Sigma-AldrichDipeptidylpeptidase IV Inhibitor IV, K579 - CAS 440100-64-1 - Calbiochem

The Dipeptidylpeptidase IV Inhibitor IV, K579, also referenced under CAS 440100-64-1, controls the biological activity of Dipeptidylpeptidase IV. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

同义词: (S)-1-(4-Methyl-1-(2-pyrimidinyl)-4-piperidylamino)acetyl-2-pyrrolidinecarbonitrile, DPP IV Inhibitor IV

Recommended Products

概述

Replacement Information

重要规格表

CAS #	Empirical Formula
440100-64-1	C₁₇H₂₄N₆O

价格及供货情况

产品目录编号	库存情况	包装	数量 / 包装	价格	数量
317642-5MGCN	正在查询供货情况...... — 目前缺货有货停产少量现货供货情况有待确认登录查看库存有货目前缺货有货其余：另行通知其余：另行通知另行通知联系客户服务 Contact Customer Service 联系客户服务联系客户服务	玻璃瓶	5 mg	正在检索价格...... 无法检索价格。最小订购数量为倍数 Maximum Quantity is 以订单确认为准更多信息您节约了 ()。 — Request Pricing 登录查看价格	查看库存情况 —	添加到收藏夹添加到收藏夹添加到我的收藏夹

Description
Overview	A cyanopyrrolidine compound that acts as a potent DPP IV inhibitor (IC₅₀ = 3, 5, 8, and 8 nM in inhibiting rat, human, monkey, and canine DDP IV, respectively). Oral administration of K579 in rats in vivo has been shown to reduce blood DPP IV activity and augment GLP-1 and insulin response after glucose intake and significantly reduce plasma glucose concentration.
Overview	Please note: 328.4 is the anhydrous molecular weight; please refer to the vial label for the lot-specific hydration and molecular weight.
Catalogue Number	317642
Brand Family	Calbiochem®
Synonyms	(S)-1-(4-Methyl-1-(2-pyrimidinyl)-4-piperidylamino)acetyl-2-pyrrolidinecarbonitrile, DPP IV Inhibitor IV

References
References	Takasaki, K., et al. 2004. Eur. J. Pharmacol. 505, 237. Takasaki, K., et al. 2004. Eur. J. Pharmacol. 486, 335. Takasaki, K., et al. 2004. J. Pharmacol. Sci. 95, 291.

Product Information
CAS number	440100-64-1
Form	Off-white to light brown solid
Hill Formula	C₁₇H₂₄N₆O
Chemical formula	C₁₇H₂₄N₆O
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Purity	≥97% by HPLC

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information
S Phrase	S: 22-24/25-36/37/39 Do not breathe dust. Avoid contact with skin and eyes. Wear suitable protective clothing, gloves and eye/face protection.

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	+2°C to +8°C
Protect from Light	Protect from light
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
317642-5MGCN	04055977216271

Documentation

Dipeptidylpeptidase IV Inhibitor IV, K579 - CAS 440100-64-1 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

Dipeptidylpeptidase IV Inhibitor IV, K579 - CAS 440100-64-1 - Calbiochem 分析证书

标题	批号
317642	输入批号

参考

参考信息概述
Takasaki, K., et al. 2004. Eur. J. Pharmacol. 505, 237. Takasaki, K., et al. 2004. Eur. J. Pharmacol. 486, 335. Takasaki, K., et al. 2004. J. Pharmacol. Sci. 95, 291.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	21-June-2023 JSW
Synonyms	(S)-1-(4-Methyl-1-(2-pyrimidinyl)-4-piperidylamino)acetyl-2-pyrrolidinecarbonitrile, DPP IV Inhibitor IV
Description	A cyanopyrrolidine compound that acts as a potent DPP IV inhibitor (IC₅₀ = 3, 5, 8, and 8 nM in inhibiting rat, human, monkey, and canine DDP IV, respectively). Oral administration of K579 in rats in vivo has been shown to reduce blood DPP IV activity and augment GLP-1 and insulin response after glucose intake and significantly reduce plasma glucose concentration.
Form	Off-white to light brown solid
Intert gas (Yes/No)	Packaged under inert gas
CAS number	440100-64-1
Chemical formula	C₁₇H₂₄N₆O
Structure formula
Purity	≥97% by HPLC
Solubility	DMSO (32 mg/ml), Ethanol (6.5 mg/ml), or 1 eq HCl (16 mg/ml) Please note: 328.4 is the anhydrous molecular weight; please refer to the vial label for the lot-specific hydration and molecular weight.
Storage	Protect from light +2°C to +8°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Toxicity	Standard Handling
References	Takasaki, K., et al. 2004. Eur. J. Pharmacol. 505, 237. Takasaki, K., et al. 2004. Eur. J. Pharmacol. 486, 335. Takasaki, K., et al. 2004. J. Pharmacol. Sci. 95, 291.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Proteases Inhibitors

此产品已添加到您的购物车。