309866 Sigma-AldrichDiltiazem, Hydrochloride - CAS 33286-22-5 - Calbiochem
Synthetic benzothiazepine that acts as an L-type Ca2+ channel antagonist.
More>> Synthetic benzothiazepine that acts as an L-type Ca2+ channel antagonist. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
同义词: L-Type Calcium Channel Blocker II
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概述
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价格及供货情况
产品目录编号 | 库存情况 | 包装 | 数量 / 包装 | 价格 | 数量 | |
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309866-100MGCN |
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塑胶安瓿;塑胶针药瓶 | 100 mg |
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Description | |
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Overview | Synthetic benzothiazepine that acts as an L-type Ca2+ channel antagonist. Similar in function to Nifedipine (Cat. No. 481981) and Verapamil (Cat. No. 676777). Has negative inotropic effects on the heart. Strongly suppresses conductance at the A-V node and automaticity at the S-A node. Has also been shown to regulate Ca2+ release from intracellular stores in neutrophils. |
Catalogue Number | 309866 |
Brand Family | Calbiochem® |
Synonyms | L-Type Calcium Channel Blocker II |
Product Information | |
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CAS number | 33286-22-5 |
ATP Competitive | N |
Form | White solid |
Hill Formula | C₂₂H₂₆N₂O₄S · HCl |
Chemical formula | C₂₂H₂₆N₂O₄S · HCl |
Hygroscopic | Hygroscopic |
Reversible | N |
Structure formula Image | |
Quality Level | MQ100 |
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Biological Information | |
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Primary Target | L-type Ca2+ channel |
Purity | ≥98% by HPLC |
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Cell permeable | N |
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Safety Information according to GHS | |
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RTECS | DL0310000 |
Safety Information | |
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R Phrase | R: 22-40 Harmful if swallowed. Limited evidence of a carcinogenic effect. |
S Phrase | S: 36 Wear suitable protective clothing. |
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Global Trade Item Number | |
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产品目录编号 | GTIN |
309866-100MGCN | 04055977216820 |
Documentation
Diltiazem, Hydrochloride - CAS 33286-22-5 - Calbiochem MSDS
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Diltiazem, Hydrochloride - CAS 33286-22-5 - Calbiochem 分析证书
标题 | 批号 |
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309866 |
参考
参考信息概述 |
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van Zwieten, P.A., and Pfaffendorf, M. 1993. J. Hypertens. Suppl. 11, S3. Rosales, C., and Brown, E.J. 1992. J. Biol. Chem. 267, 1443. Julian, D.G. 1987. Am. J. Cardiol. 59, 37J. Campbell, K.P., et al. 1986. Proc. Natl. Acad. Sci. USA 83, 2792. Gallizzi, J.P., et al. 1986. J. Biol. Chem. 261, 1393. Garcia, M.L., et al. 1986. J. Biol. Chem. 261, 8146. |