数量	产品目录编号	订购说明	数量 / 包装	公开价
			96-Well Plate

数量	产品目录编号	订购说明	数量 / 包装	公开价
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

376650 Sigma-AldrichD-erythro-Sphingosine, N-Hexanoyl- - CAS 124753-97-5 - Calbiochem

Biologically active, cell-permeable, non-physiological ceramide analog.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
小册子
Data Sheet

同义词: C₆ Ceramide

Recommended Products

概述

Replacement Information

重要规格表

CAS #	Empirical Formula
124753-97-5	C₂₄H₄₇NO₃

价格及供货情况

产品目录编号	库存情况	包装	数量 / 包装	价格	数量
376650-5MGCN	正在查询供货情况...... — 目前缺货有货停产少量现货供货情况有待确认登录查看库存有货目前缺货有货其余：另行通知其余：另行通知另行通知联系客户服务 Contact Customer Service 联系客户服务联系客户服务	塑胶安瓿;塑胶针药瓶	5 mg	正在检索价格...... 无法检索价格。最小订购数量为倍数 Maximum Quantity is 以订单确认为准更多信息您节约了 ()。 — Request Pricing 登录查看价格	查看库存情况 —	添加到收藏夹添加到收藏夹添加到我的收藏夹

Description
Overview	Biologically active, cell-permeable, non-physiological ceramide analog. Induces a dramatic arrest in the G₀/G₁ phase of the cell cycle. Activates MAP kinase. Activates protein phosphatase 2A (PP2A) at 10 nM. Inhibits diacylglycerol accumulation and phospholipase D (PLD) activation in fibroblasts. Induces apoptosis in MOLT-4 leukemia cells.
Catalogue Number	376650
Brand Family	Calbiochem®
Synonyms	C₆ Ceramide

References
References	Jayadev, S., et al. 1995. J. Biol. Chem. 270, 2047. Venable, M.E., et al. 1994. J. Biol. Chem. 269, 26040. Dobrowsky, R.T., et al. 1993. J. Biol. Chem. 268, 15523. Raines, M.A., et al. 1993. J. Biol. Chem. 268, 14572. Dobrowsky, R.T., and Hannun, Y.A. 1992. J. Biol. Chem. 267, 5048.

Product Information
CAS number	124753-97-5
ATP Competitive	N
Form	White waxy solid
Hill Formula	C₂₄H₄₇NO₃
Chemical formula	C₂₄H₄₇NO₃
Reversible	N
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Primary Target	MAP kinase, protein phosphatase 2A (PP2A)
Primary Target IC<sub>50</sub>	Effective concentration: 10 nM in activating protein phosphatase 2A (PP2A)
Purity	≥95% by TLC

Physicochemical Information
Cell permeable	Y

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information
R Phrase	R: 36/37/38 Irritating to eyes, respiratory system and skin.
S Phrase	S: 26-36 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing.

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Irritant
Storage	-20°C
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
376650-5MGCN	04055977212952

Documentation

D-erythro-Sphingosine, N-Hexanoyl- - CAS 124753-97-5 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

D-erythro-Sphingosine, N-Hexanoyl- - CAS 124753-97-5 - Calbiochem 分析证书

标题	批号
376650	输入批号

参考

参考信息概述
Jayadev, S., et al. 1995. J. Biol. Chem. 270, 2047. Venable, M.E., et al. 1994. J. Biol. Chem. 269, 26040. Dobrowsky, R.T., et al. 1993. J. Biol. Chem. 268, 15523. Raines, M.A., et al. 1993. J. Biol. Chem. 268, 14572. Dobrowsky, R.T., and Hannun, Y.A. 1992. J. Biol. Chem. 267, 5048.

小册子

标题
Bioactive Lipids Technical Bulletin
Caspases and other Apoptosis Related Tools Brochure

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	25-September-2019 JSW
Synonyms	C₆ Ceramide
Description	Biologically active, cell-permeable, nonphysiological ceramide analog. Stimulates cytosolic serine/threonine protein phosphatase in T9 cells and induces phosphorylation on Thr-669 in A-431 cells by stimulation of ceramide-activated protein kinase. Induces a dramatic arrest in the G_o/G₁ phase of the cell cycle. Activates MAP kinase. Activates protein phosphatase 2A (PP2A) at 10 nM. Inhibits diacylglycerol accumulation and phospholipase D activation in fibroblasts. Induces apoptosis in Molt-4 leukemia cells.
Form	White waxy solid
CAS number	124753-97-5
Chemical formula	C₂₄H₄₇NO₃
Structure formula
Purity	≥95% by TLC
Solubility	DMSO or Ethanol (25 mg/ml)
Storage	-20°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
Toxicity	Irritant
References	Jayadev, S., et al. 1995. J. Biol. Chem. 270, 2047. Venable, M.E., et al. 1994. J. Biol. Chem. 269, 26040. Dobrowsky, R.T., et al. 1993. J. Biol. Chem. 268, 15523. Raines, M.A., et al. 1993. J. Biol. Chem. 268, 14572. Dobrowsky, R.T., and Hannun, Y.A. 1992. J. Biol. Chem. 267, 5048.

种类

Life Science Research > Inhibitors and Biochemicals > Biochemicals > Lipids > Sphingolipids

此产品已添加到您的购物车。