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			96-Well Plate

数量	产品目录编号	订购说明	数量 / 包装	公开价
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

250233 Sigma-AldrichCytochalasin B, Helminthosporium dematioideum - CAS 14930-96-2 - Calbiochem

Cytochalasin B, Helminthosporium dematioideum - CAS 14930-96-2, is a cell-permeable fungal toxin that inhibits cytoplasmic division by blocking the formation of contractile microfilaments.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

Primary Target: Blocking the formation of contractile microfilaments

Recommended Products

概述

Replacement Information

重要规格表

CAS #	Empirical Formula
14930-96-2	C₂₉H₃₇NO₅

价格及供货情况

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Description
Overview	Cell-permeable fungal toxin. Inhibits cytoplasmic division by blocking the formation of contractile microfilaments. Inhibits cell movement and induces nuclear extrusion. Shortens actin filaments by blocking monomer addition at the fast-growing end of polymers. Inhibits glucose transport and platelet aggregation. Blocks adenosine-induced apoptotic body formation without affecting activation of endogenous ADP-ribosylation in leukemia HL-60 cells.
Catalogue Number	250233
Brand Family	Calbiochem®

References
References	Tanaka, Y., et al. 1994. Exp. Cell Res. 213, 242. Theodoropoulos, P.A., et al. 1994. Biochem. Pharmacol. 47, 1875. Benya, P.D., and Padilla, S.R. 1993. Exp. Cell Res. 204, 268. Cairns, M.T., et al. 1991. J. Biol. Chem. 266, 8176. Nowak, D. 1990. Biomed. Biochim. Acta 49, 353. Wang, F., et al. 1990. Biochem. Biophys. Res. Commun. 171, 543. Edwards, S.W., and Lloyd, D. 1988. FEBS Lett. 227, 39.

References

Tanaka, Y., et al. 1994. Exp. Cell Res. 213, 242.
Theodoropoulos, P.A., et al. 1994. Biochem. Pharmacol. 47, 1875.
Benya, P.D., and Padilla, S.R. 1993. Exp. Cell Res. 204, 268.
Cairns, M.T., et al. 1991. J. Biol. Chem. 266, 8176.
Nowak, D. 1990. Biomed. Biochim. Acta 49, 353.
Wang, F., et al. 1990. Biochem. Biophys. Res. Commun. 171, 543.
Edwards, S.W., and Lloyd, D. 1988. FEBS Lett. 227, 39.

Product Information
CAS number	14930-96-2
ATP Competitive	N
Form	White solid
Hill Formula	C₂₉H₃₇NO₅
Chemical formula	C₂₉H₃₇NO₅
Reversible	N
Structure formula Image
Quality Level	MQ100

Applications
Application	Cytochalasin B, Helminthosporium dematioideum - CAS 14930-96-2, is a cell-permeable fungal toxin that inhibits cytoplasmic division by blocking the formation of contractile microfilaments.

Biological Information
Primary Target	Blocking the formation of contractile microfilaments
Purity	≥98% by HPLC

Physicochemical Information
Cell permeable	Y

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS
RTECS	RO0205000

Safety Information
R Phrase	R: 26/27/28-63 Very toxic by inhalation, in contact with skin and if swallowed. Possible risk of harm to the unborn child.
S Phrase	S: 22-36/37/39-45 Do not breathe dust. Wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Highly Toxic & Carcinogenic / Teratogenic
Hazardous Materials Attention:	Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage	-20°C
Protect from Light	Protect from light
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution store in the refrigerator (4°C). Stock solutions are stable for up to 3 months at 4°C.

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
250233-5MGCN	04055977199147

Documentation

Cytochalasin B, Helminthosporium dematioideum - CAS 14930-96-2 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

Cytochalasin B, Helminthosporium dematioideum - CAS 14930-96-2 - Calbiochem 分析证书

标题	批号
250233	输入批号

参考

参考信息概述
Tanaka, Y., et al. 1994. Exp. Cell Res. 213, 242. Theodoropoulos, P.A., et al. 1994. Biochem. Pharmacol. 47, 1875. Benya, P.D., and Padilla, S.R. 1993. Exp. Cell Res. 204, 268. Cairns, M.T., et al. 1991. J. Biol. Chem. 266, 8176. Nowak, D. 1990. Biomed. Biochim. Acta 49, 353. Wang, F., et al. 1990. Biochem. Biophys. Res. Commun. 171, 543. Edwards, S.W., and Lloyd, D. 1988. FEBS Lett. 227, 39.

参考信息概述

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	06-April-2009 JSW
Description	Cell-permeable fungal toxin. Inhibits cytoplasmic division by blocking the formation of contractile microfilaments. Inhibits cell movement and induces nuclear extrusion. Shortens actin filaments by blocking monomer addition at the fast growing end of polymers. Inhibits glucose transport and platelet aggregation. Blocks adenosine-induced apoptotic body formation without affecting activation of endogenous ADP-ribosylation in leukemia HL-60 cells.
Form	White solid
CAS number	14930-96-2
RTECS	RO0205000
Chemical formula	C₂₉H₃₇NO₅
Structure formula
Purity	≥98% by HPLC
Solubility	DMSO (50 mg/ml) or Methanol (20 mg/ml). Poor quality DMSO will cause degradation of the product, so high quality DMSO is recommended.
Storage	Protect from light -20°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution store in the refrigerator (4°C). Stock solutions are stable for up to 3 months at 4°C.
Toxicity	Highly Toxic & Carcinogenic / Teratogenic
Merck USA index	14, 2790
References	Tanaka, Y., et al. 1994. Exp. Cell Res. 213, 242. Theodoropoulos, P.A., et al. 1994. Biochem. Pharmacol. 47, 1875. Benya, P.D., and Padilla, S.R. 1993. Exp. Cell Res. 204, 268. Cairns, M.T., et al. 1991. J. Biol. Chem. 266, 8176. Nowak, D. 1990. Biomed. Biochim. Acta 49, 353. Wang, F., et al. 1990. Biochem. Biophys. Res. Commun. 171, 543. Edwards, S.W., and Lloyd, D. 1988. FEBS Lett. 227, 39.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Extracellular Matrix, Adhesion and Cytoskeletal Research Tools

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