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05-23-0050 Sigma-AldrichCorticotropin Releasing Factor, Human and Rat - CAS 86784-80-7 - Calbiochem

An immunomodulatory neuropeptide that acts to release ACTH from the anterior pituitary and stimulates the sympathetic nervous system and adrenal medulla.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

同义词: CRF

Primary Target: An immunomodulatory neuropeptide

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概述

Replacement Information

重要规格表

CAS #	Empirical Formula
86784-80-7	C₂₀₈H₃₄₄N₆₀O₆₃S₂

价格及供货情况

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Description
Overview	An immunomodulatory neuropeptide that acts to release ACTH from the anterior pituitary and stimulates the sympathetic nervous system and adrenal medulla. Functions by reducing hyperpolarizations. Acts as a functional antagonist of inflammatory mediators.
Catalogue Number	05-23-0050
Brand Family	Calbiochem®
Synonyms	CRF

References
References	Barmack, N.H., and Errico, P. 1993. J. Neurosci. 13, 4647. Wei, E.T., et al. 1993. Ciba Found. Symp. 172, 258. Smith, E.M., et al. 1986. Nature 321, 881. Udelsman, R., et al. 1986. Nature 319, 147.

Product Information
CAS number	86784-80-7
ATP Competitive	N
Form	White to off-white lyophilized solid
Formulation	Supplied as an acetate salt.
Hill Formula	C₂₀₈H₃₄₄N₆₀O₆₃S₂
Chemical formula	C₂₀₈H₃₄₄N₆₀O₆₃S₂
Hygroscopic	Hygroscopic
Reversible	N
Sold on the basis of peptide content	Y
Quality Level	MQ100

Applications

Biological Information
Primary Target	An immunomodulatory neuropeptide
Purity	≥97% by HPLC

Physicochemical Information
Cell permeable	N
Peptide Content	Y
Peptide Sequence	H-Ser-Glu-Glu-Pro-Pro-Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Gln-Ala-His-Ser-Asn-Arg-Lys-Leu-Met-Glu-Ile-Ile-NH₂

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS
RTECS	GM7925000

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Hygroscopic	Hygroscopic
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
05-23-0050-1MGCN	04055977206890

Documentation

Corticotropin Releasing Factor, Human and Rat - CAS 86784-80-7 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

Corticotropin Releasing Factor, Human and Rat - CAS 86784-80-7 - Calbiochem 分析证书

标题	批号
05-23-0050	输入批号

参考

参考信息概述
Barmack, N.H., and Errico, P. 1993. J. Neurosci. 13, 4647. Wei, E.T., et al. 1993. Ciba Found. Symp. 172, 258. Smith, E.M., et al. 1986. Nature 321, 881. Udelsman, R., et al. 1986. Nature 319, 147.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	02-April-2009 JSW
Synonyms	CRF
Description	Releases ACTH from the anterior pituitary and stimulates the sympathetic nervous system and adrenal medulla. Functions by reducing hyperpolarizations. Acts as a functional antagonist of inflammatory mediators.
Form	White to off-white lyophilized solid
Formulation	Supplied as an acetate salt.
CAS number	86784-80-7
RTECS	GM7925000
Chemical formula	C₂₀₈H₃₄₄N₆₀O₆₃S₂
Peptide Sequence	H-Ser-Glu-Glu-Pro-Pro-Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Gln-Ala-His-Ser-Asn-Arg-Lys-Leu-Met-Glu-Ile-Ile-NH₂
Purity	≥97% by HPLC
Solubility	5% NH₄OH (prepared with H₂O) (1 mg/ml)
Storage	-20°C Hygroscopic
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity	Standard Handling
References	Barmack, N.H., and Errico, P. 1993. J. Neurosci. 13, 4647. Wei, E.T., et al. 1993. Ciba Found. Symp. 172, 258. Smith, E.M., et al. 1986. Nature 321, 881. Udelsman, R., et al. 1986. Nature 319, 147.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Neurochemicals > Neuropeptides

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