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234567
Sigma-AldrichConcanavalin A, Canavalia ensiformis
Concanavalin A, Canavalia ensiformis, CAS 11028-71-0, is a carbohydrate-binding protein that agglutinates various animal cells. Restores the growth pattern of tumor cells to that of normal cells.
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Concanavalin A, Canavalia ensiformis MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Carbohydrate-binding protein that agglutinates various animal cells. Also known to restore the growth pattern of tumor cells to that of normal cells. T lymphocyte activator. Has binding sites for metal ions, α-D-mannose, and α-D-glucose.
Catalogue Number
234567
Brand Family
Calbiochem®
Synonyms
Con A, Jack Bean Hemagglutinin
References
References
Gantner, F., et al. 1995. Hepatology 21, 190.
Product Information
CAS number
11028-71-0
Activity
Agglutination Activity: ≤20 µg Lectin/ml as determined from serial dilutions of a 1 mg/mL solution (this activity is the lowest conc. to agglutinate a 2% suspension of human erythrocytes after 1 hr incubation at 25°C; requires type A human blood)
Harmful by inhalation, in contact with skin and if swallowed. Limited evidence of a carcinogenic effect. May cause sensitization by inhalation and skin contact.
S Phrase
S: 36
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code
Ambient Temperature Only
Toxicity
Harmful
Storage
+2°C to +8°C
Do not freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C) or add 0.08% NaN₃ and refrigerate (4°C). Stock solutions are stable for up to 6 months at -20°C or for up to 3 months at 4°C.
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
05-September-2017 JSW
Synonyms
Con A, Jack Bean Hemagglutinin
Description
Carbohydrate-binding protein that agglutinates various animal cells. Also known to restore the growth pattern of tumor cells to that of normal cells. T lymphocyte activator. Has binding sites for metal ions, α-D-mannose, and α-D-glucose. Has a pI of 4.5-5.5.
Form
Lyophilized
Formulation
Salt-free.
CAS number
11028-71-0
RTECS
GK6890000
Activity
Agglutination Activity: ≤20 µg Lectin/ml as determined from serial dilutions of a 1 mg/mL solution (this activity is the lowest conc. to agglutinate a 2% suspension of human erythrocytes after 1 hr incubation at 25°C; requires type A human blood)
Solubility
To dissolve, add Con A slowly to a solution of 10 mM HEPES buffered saline, 100 µM CaCl₂, pH 8.5. Allow the lectin to dissolve without agitation.
Storage
+2°C to +8°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C) or add 0.08% NaN₃ and refrigerate (4°C). Stock solutions are stable for up to 6 months at -20°C or for up to 3 months at 4°C.
