数量	产品目录编号	订购说明	数量 / 包装	公开价
			96-Well Plate

数量	产品目录编号	订购说明	数量 / 包装	公开价
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

204897 Sigma-AldrichComplement C4b, Human

Complement C4b, Human, is a native, 193 kDa glycoprotein composed of the modified C4 α-chain (α') and intact β- and γ-chains complement component.

Complement C4b, Human MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

View Products on Sigmaaldrich.com

Recommended Products

概述

Replacement Information

价格及供货情况

产品目录编号	库存情况	包装	数量 / 包装	价格	数量
204897-250UGCN	正在查询供货情况...... — 目前缺货有货停产少量现货供货情况有待确认登录查看库存有货目前缺货有货其余：另行通知其余：另行通知另行通知联系客户服务 Contact Customer Service 联系客户服务联系客户服务	塑胶安瓿;塑胶针药瓶	250 μg	正在检索价格...... 无法检索价格。最小订购数量为倍数 Maximum Quantity is 以订单确认为准更多信息您节约了 ()。 — Request Pricing 登录查看价格	查看库存情况 —	添加到收藏夹添加到收藏夹添加到我的收藏夹

Description
Overview	Native, human C4b complement component. Cleavage of the C4 α-chain at peptide bond 77 by activated C1 enzyme results in the production of C4a (M.W. 8,758) and C4b (M.W. 193,000) fragments. The C4b fragment is a glycoprotein composed of the modified C4 α-chain (α′) and intact β- and γ-chains. Like C3b, C4b has the transient ability to form a covalent ester bond with a variety of target cell surfaces. Once bound to the target surface, C4b becomes an essential non-enzymatic subunit of the classical pathway C3 cleaving enzyme (C4b,C2a). In addition, surface bound C4b has opsonic and immune adherence activities which are mediated via binding to the CR1 (CD35) complement receptor which is found on a variety of inflammatory cells.
Catalogue Number	204897
Brand Family	Calbiochem®

References
References	Weisman, H.F., et al. 1990. Science 249, 146. Holers, M.V., et al. 1985. Immunology Today 6, 188.

Product Information
Form	Liquid
Formulation	In PBS, pH 7.2.
Preservative	None
Quality Level	MQ100

Applications

Biological Information
Purity	≥95% by SDS-PAGE
Source	Prepared from plasma of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Concentration Label	Please refer to vial label for lot-specific concentration

Physicochemical Information
Contaminants	IgG, IgA, IgM, Factor B, Factor H, C3, ceruloplasmin, or albumin: ≤trace amounts

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Dry Ice Only
Toxicity	Standard Handling
Storage	≤ -70°C
Avoid freeze/thaw	Avoid freeze/thaw
Do not freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-70°C).

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
204897-250UGCN	04055977219852

Documentation

Complement C4b, Human MSDS

职位
物料安全数据表 (MSDS)

Complement C4b, Human 分析证书

标题	批号
204897	输入批号

参考

参考信息概述
Weisman, H.F., et al. 1990. Science 249, 146. Holers, M.V., et al. 1985. Immunology Today 6, 188.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	27-May-2008 RFH
Description	Native, human C4b complement component. Cleavage of the C4 α-chain at peptide bond 77 by activated C1 enzyme results in the production of C4a (M.W. 8,758) and C4b (M.W. 193,000) fragments. The C4b fragment is a glycoprotein composed of the modified C4 α-chain (α') and intact β- and γ-chains. Like C3b, C4b has the transient ability to form a covalent ester bond with a variety of target cell surfaces. Once bound to the target surface, C4b becomes an essential non-enzymatic subunit of the classical pathway C3 cleaving enzyme (C4b,C2a). In addition, surface bound C4b has opsonic and immune adherence activities, which are mediated via binding to the CR1 (CD35) complement receptor, which is found on a variety of inflammatory cells.
Form	Liquid
Formulation	In PBS, pH 7.2.
Concentration Label	Please refer to vial label for lot-specific concentration
Source	Prepared from plasma of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Purity	≥95% by SDS-PAGE
Contaminants	IgG, IgA, IgM, Factor B, Factor H, C3, ceruloplasmin, or albumin: ≤trace amounts
Preservative	None
Storage	Avoid freeze/thaw ≤ -70°C
Do Not Freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-70°C).
Toxicity	Standard Handling
References	Weisman, H.F., et al. 1990. Science 249, 146. Holers, M.V., et al. 1985. Immunology Today 6, 188.

种类

Life Science Research > Proteins and Enzymes > Other Proteins

此产品已添加到您的购物车。