Custom Premix Selecting "Custom Premix" option means that all of the beads you have chosen will be premixed in manufacturing before the kit is sent to you.
Native, human des-Arg C3 complement component. Single chain, 76 amino acid peptide. Once the C3a peptide has been produced in human plasma or serum, it is rapidly converted to C3a des-Arg upon removal of the C-terminal arginine by endogenous serum carboxypeptidase N. This enzymatic process is considered to be a major mechanism for controlling C3a function in vivo because C3a des-Arg has <1% of the biological activity expressed by the C3a peptide. Therefore, C3a des-Arg can serve as a negative control molecule in experiments involved with the biological activities of the intact C3a anaphylatoxin peptide.
Catalogue Number
204884
Brand Family
Calbiochem®
References
References
Kajita, T. and Hugli, T.E. 1991. Am. J. Pathol. 138, 1359. Bokish, V.A. and Muller-Eberhard, H.J. 1970. J. Clin. Invest.49, 2427.
Kajita, T. and Hugli, T.E. 1991. Am. J. Pathol. 138, 1359. Bokish, V.A. and Muller-Eberhard, H.J. 1970. J. Clin. Invest.49, 2427.
数据表
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
16-December-2018 JSW
Description
Native, human des-Arg C3 complement component. Single chain, 76 amino acid peptide. Once the C3a peptide has been produced in human plasma or serum, it is rapidly converted to C3a des-Arg upon removal of the C-terminal arginine by endogenous serum carboxypeptidase N. This enzymatic process is considered to be a major mechanism for controlling C3a function in vivo because C3a des-Arg has <1% of the biological activity expressed by the C3a peptide. Therefore, C3a des-Arg can serve as a negative control molecule in experiments involved with the biological activities of the intact C3a anaphylatoxin peptide.
Form
Liquid
Formulation
In PBS, pH 7.2.
Concentration Label
Please refer to vial label for lot-specific concentration
Source
Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Purity
≥90% by SDS-PAGE
Biological activity
Ileum contraction assay: negative
Storage
Avoid freeze/thaw
≤ -70°C
Do Not Freeze
Ok to freeze
Special Instructions
Following initial thaw, aliquot and freeze (-70°C).
Toxicity
Standard Handling
References
Kajita, T. and Hugli, T.E. 1991. Am. J. Pathol. 138, 1359. Bokish, V.A. and Muller-Eberhard, H.J. 1970. J. Clin. Invest.49, 2427.
