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233493
Sigma-AldrichCoagulation Factor α-XIIa, Human Plasma
Coagulation Factor α-XIIa, Human Plasma, is a native coagulation factor α-XIIa prepared from homogeneous Factor XII using dextran sulfate. Dextran sulfate is removed after activation.
More>>Coagulation Factor α-XIIa, Human Plasma, is a native coagulation factor α-XIIa prepared from homogeneous Factor XII using dextran sulfate. Dextran sulfate is removed after activation. Less<<
Coagulation Factor α-XIIa, Human Plasma MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Native coagulation factor α-XIIa from human plasma prepared from homogeneous Factor XII using dextran sulfate. Dextran sulfate is removed after activation. α-XIIa is a serine protease responsible for activation of Factor XI to Factor XIa. Factor XIIa and prekallikrein are thought to be involved in a reciprocal activation mechanism whereby Factor XIIa activates prekallikrein to kallikrein, which in turn converts Factor XII to Factor XIIa.
Catalogue Number
233493
Brand Family
Calbiochem®
References
Product Information
Form
Liquid
Formulation
In 150 mM NaCl, 4 mM sodium acetate buffer, pH 5.3.
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
06-June-2008 RFH
Description
Native coagulation factor α-XIIa from human plasma prepared from homogeneous Factor XII using dextran sulfate. Dextran sulfate is removed after activation. α-XIIa is a serine protease responsible for activation of Factor XI to Factor XIa. Factor XIIa and prekallikrein are thought to be involved in a reciprocal activation mechanism whereby Factor XIIa activates prekallikrein to kallikrein, which in turn converts Factor XII to Factor XIIa.
Form
Liquid
Formulation
In 150 mM NaCl, 4 mM sodium acetate buffer, pH 5.3.
Concentration Label
Please refer to vial label for lot-specific concentration
Source
Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Purity
homogeneous by SDS-PAGE
Specific activity
50 units/mg protein (clotting assay). Clotting activity is determined by comparison to a standard curve produced using normal pooled human plasma
Storage
Avoid freeze/thaw
≤ -70°C
Do Not Freeze
Ok to freeze
Special Instructions
Following initial thaw, aliquot and freeze (-70°C).
