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233155 MilliporeCleland’s Reagent - CAS 3483-12-3 - Calbiochem

A protective agent for SH groups. Cyclizes as it reduces disulfides to thiols, so reaction is "driven" to completion. Does not contain waxy surfactant found in many other preparations. Oxidized dithiothreitol: ≤0.5%.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
小册子
Data Sheet

同义词: DTT, Dithiothreitol

Recommended Products

概述

Replacement Information

重要规格表

CAS #	Empirical Formula
3483-12-3	C₄H₁₀O₂S₂

价格及供货情况

产品目录编号	库存情况	包装	数量 / 包装	价格	数量
233155-100GMCN	正在查询供货情况...... — 目前缺货有货停产少量现货供货情况有待确认登录查看库存有货目前缺货有货其余：另行通知其余：另行通知另行通知联系客户服务 Contact Customer Service 联系客户服务联系客户服务	玻璃瓶	100 gm	正在检索价格...... 无法检索价格。最小订购数量为倍数 Maximum Quantity is 以订单确认为准更多信息您节约了 ()。 — Request Pricing 登录查看价格	查看库存情况 —	添加到收藏夹添加到收藏夹添加到我的收藏夹
233155-1KGCN	正在查询供货情况...... — 目前缺货有货停产少量现货供货情况有待确认登录查看库存有货目前缺货有货其余：另行通知其余：另行通知另行通知联系客户服务 Contact Customer Service 联系客户服务联系客户服务	玻璃瓶	1 kg	正在检索价格...... 无法检索价格。最小订购数量为倍数 Maximum Quantity is 以订单确认为准更多信息您节约了 ()。 — Request Pricing 登录查看价格	查看库存情况 —	添加到收藏夹添加到收藏夹添加到我的收藏夹
233155-25GMCN	正在查询供货情况...... — 目前缺货有货停产少量现货供货情况有待确认登录查看库存有货目前缺货有货其余：另行通知其余：另行通知另行通知联系客户服务 Contact Customer Service 联系客户服务联系客户服务	玻璃瓶	25 gm	正在检索价格...... 无法检索价格。最小订购数量为倍数 Maximum Quantity is 以订单确认为准更多信息您节约了 ()。 — Request Pricing 登录查看价格	查看库存情况 —	添加到收藏夹添加到收藏夹添加到我的收藏夹

Description
Overview	A protective agent for SH groups. Cyclizes as it reduces disulfides to thiols, so reaction is "driven" to completion. Does not contain waxy surfactant found in many other preparations.
Overview	Oxidized dithiothreitol: ≤0.5%.
Catalogue Number	233155
Brand Family	Calbiochem®
Synonyms	DTT, Dithiothreitol

References
References	Gailis, L. 1994. Eur. J. Pharmacol. 292, 39. Lauriault, V.V.M., and O'Brien, P.J. 1991. Mol. Pharmacol. 40, 125. Klonne, D.R., and Johnson, D.R. 1988. Toxicol. Lett. 42, 199. Zahler, W.L., and Cleland, W.W. 1968. J. Biol. Chem. 243, 716. Cleland, W.W. 1964. Biochemistry 3, 480.

Product Information
CAS number	3483-12-3
Form	White to off-white powder
Hill Formula	C₄H₁₀O₂S₂
Chemical formula	C₄H₁₀O₂S₂
Quality Level	MQ100

Applications

Biological Information
Purity	≥97% by titration

Physicochemical Information
Contaminants	Heavy metals: ≤1 ppm
Heavy metals	<1 ppm

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS
RTECS	EK1610000

Safety Information
R Phrase	R: 22-36/38 Harmful if swallowed. Irritating to eyes and skin.
S Phrase	S: 36-26 Wear suitable protective clothing. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Harmful
Storage	+2°C to +8°C
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot, purge with inert gas, and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
233155-100GMCN	07790788054274
233155-1KGCN	04055977217681
233155-25GMCN	04055977217711

Documentation

Cleland’s Reagent - CAS 3483-12-3 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

Cleland’s Reagent - CAS 3483-12-3 - Calbiochem 分析证书

标题	批号
233155	输入批号

参考

参考信息概述
Gailis, L. 1994. Eur. J. Pharmacol. 292, 39. Lauriault, V.V.M., and O'Brien, P.J. 1991. Mol. Pharmacol. 40, 125. Klonne, D.R., and Johnson, D.R. 1988. Toxicol. Lett. 42, 199. Zahler, W.L., and Cleland, W.W. 1968. J. Biol. Chem. 243, 716. Cleland, W.W. 1964. Biochemistry 3, 480.

小册子

标题
Bulk Product Guide

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	29-April-2008 RFH
Synonyms	DTT, Dithiothreitol
Description	DTT is a water-soluble protective reagent for sulfhydryl groups. It maintains monothiols in the reduced state and reduces disulfides quantitatively. Most widely used for the study of disulfide exchange reactions of protein disulfides. DTT readily permeates cell membranes. Protects protein sulfhydryls and restores enzyme activity lost by the oxidation of sulfhydryl groups in vitro. As a reducing agent, it cyclizes as it reduces disulfides to thiols, so the reaction is "driven" to completion without using large excesses of reductant. If free thiols are to be assayed later, excess reductant must be removed by dialysis or some other appropriate method. Alternatively, an immobilized form of DTT (REDUCTACRYL^™ Reagent, Cat. No. 233157) can be used. Oxidized dithiothreitol: ≤0.5%.
Form	White to off-white powder
Intert gas (Yes/No)	Packaged under inert gas
CAS number	3483-12-3
RTECS	EK1610000
Chemical formula	C₄H₁₀O₂S₂
Purity	≥97% by titration
Contaminants	Heavy metals: ≤1 ppm
Solubility	Ethanol or H₂O (30 mg/ml)
Storage	+2°C to +8°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot, purge with inert gas, and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity	Harmful
Merck USA index	14, 3376
References	Gailis, L. 1994. Eur. J. Pharmacol. 292, 39. Lauriault, V.V.M., and O'Brien, P.J. 1991. Mol. Pharmacol. 40, 125. Klonne, D.R., and Johnson, D.R. 1988. Toxicol. Lett. 42, 199. Zahler, W.L., and Cleland, W.W. 1968. J. Biol. Chem. 243, 716. Cleland, W.W. 1964. Biochemistry 3, 480.

种类

Life Science Research > Inhibitors and Biochemicals > Biochemicals > Life Science Relevant Organics and Inorganics > Reducing Agents

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