Custom Premix Selecting "Custom Premix" option means that all of the beads you have chosen will be premixed in manufacturing before the kit is sent to you.
A potent uptake inhibitor highly selective for 5-HT transporter without effect on noradrenalin or dopamine uptake (IC50 = 1.8, 8800 and 41000 nM for 5-HT, noradrenalin and dopamine, respectively). Clinically prescribed as an antidepressant drug. Widely used in research related to depressive disorders.
Catalogue Number
506238
Brand Family
Calbiochem®
Synonyms
5-HT Transporter Inhibitor, Citalopram, Celexa
References
References
Garriock, A., et al., 2010. Bio. Psychiatry.67, 133. Gabriel, J.P., et al. 2009. J. Neurosci.29,10387. Torres, G.E., et al. 2003. Nat. Rev. Neurosci.4, 13.
Garriock, A., et al., 2010. Bio. Psychiatry.67, 133. Gabriel, J.P., et al. 2009. J. Neurosci.29,10387. Torres, G.E., et al. 2003. Nat. Rev. Neurosci.4, 13.
数据表
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
15-November-2013 JSW
Synonyms
5-HT Transporter Inhibitor, Citalopram, Celexa
Description
A potent uptake inhibitor highly selective for 5-HT transporter without effect on noradrenalin or dopamine uptake (IC50 = 1.8, 8800 and 41000 nM for 5-HT, noradrenalin and dopamine, respectively). Clinically prescribed as an antidepressant drug. Widely used in research related to depressive disorders.
Form
White solid
CAS number
59729-32-7
Chemical formula
C₂₀H₂₁FN₂O·HBr
Structure formula
Purity
≥98% by HPLC
Solubility
Ethanol (50 mM) or H₂O (10 mM)
Storage
Protect from light
+2°C to +8°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°). Stock solutions are stable for up to 3 months at -20°C.
Toxicity
Harmful
References
Garriock, A., et al., 2010. Bio. Psychiatry.67, 133. Gabriel, J.P., et al. 2009. J. Neurosci.29,10387. Torres, G.E., et al. 2003. Nat. Rev. Neurosci.4, 13.