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219502 Cathepsin L Inhibitor, CAA0225 - Calbiochem

概述

重要规格表

Empirical Formula
C₂₈H₂₉N₃O₅

价格及供货情况

产品目录编号 库存情况包装 数量 / 包装 价格 数量
219502-1MGCN
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      Description
      OverviewAn epoxysuccinyl peptide highly selective for rat liver cathepsin L (IC50 = 1.9 nM), while exhibiting little to no effect on rat liver cathepsin B at concentrations higher than 1000-5000 nM, in vitro. During autophagy, it has been shown through immunoblotting that CAA0225 (10 µg/ml) effectively inhibits the degradation of LC3-II and GABARAP compared to control, in nutrient-deprived HeLa and Huh-7 cells.
      Catalogue Number219502
      Brand Family Calbiochem®
      References
      ReferencesTakahashi, K., et al. 2009. Biol. Pharm. Bull. 32, 475.
      Ueno, T., et al. 2009. Autophagy 5, 878.
      Product Information
      FormWhite solid
      Hill FormulaC₂₈H₂₉N₃O₅
      Chemical formulaC₂₈H₂₉N₃O₅
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Purity≥ 95% by HPLC
      Storage and Shipping Information
      Ship Code Shipped with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Global Trade Item Number
      产品目录编号 GTIN
      219502-1MGCN 04055977218039