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219419 Cathepsin Inhibitor III - Calbiochem

The Cathepsin Inhibitor III controls the biological activity of Cathepsin. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Cathepsin Inhibitor III - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

同义词: Z-FG-NHO-BzOME

Primary Target: cathepsin B
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219419
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概述

Replacement Information

重要规格表

Empirical Formula
C₂₇H₂₇N₃O₇

价格及供货情况

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      		 塑胶安瓿;塑胶针药瓶 1 mg
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      Description
      OverviewCysteine protease inhibitor. Selectively inhibits cathepsin B (k2/Ki = 1 x 104 M-1 sec-1), cathepsin L (k2/Ki = 1.5 x 105 M-1 sec-1), cathepsin S (k2/Ki = 6.6 x 104 M-1 sec-1), and papain (k2/Ki = 1 x 103 M-1 sec-1).
      Half-life in buffered solution (pH 5-9) = 37 h (30°C); 300 h (0°C).
      Catalogue Number219419
      Brand Family Calbiochem®
      SynonymsZ-FG-NHO-BzOME
      References
      ReferencesDemuth, H.-U., et al. 1996. Biochim. Biophys. Acta 1295, 179.
      Brömme, D., and Demuth, H.-U. 1994. Methods Enzymol. 244, 671.
      Product Information
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₂₇H₂₇N₃O₇
      Chemical formulaC₂₇H₂₇N₃O₇
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetcathepsin B
      Primary Target K<sub>i</sub>k₂/Ki = 1 x 10⁴ M⁻¹ sec⁻¹
      Purity>90% by HPLC
      Physicochemical Information
      Cell permeableN
      Peptide SequenceZ-Phe-Gly-NHO-Bz-pOMe
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +15°C to +30°C
      Protect from Light Protect from light
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      产品目录编号 GTIN
      219419-1MGCN 04055977218336

      Documentation

      Cathepsin Inhibitor III - Calbiochem MSDS

      职位

      物料安全数据表 (MSDS) 

      Cathepsin Inhibitor III - Calbiochem 分析证书

      标题批号
      219419

      参考

      参考信息概述
      Demuth, H.-U., et al. 1996. Biochim. Biophys. Acta 1295, 179.
      Brömme, D., and Demuth, H.-U. 1994. Methods Enzymol. 244, 671.

      小册子

      标题
      Cathepsins and Related Products Technical Bulletin
      数据表

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision27-September-2007 RFH
      SynonymsZ-FG-NHO-BzOME
      DescriptionCysteine protease inhibitor. Selectively inhibits cathepsin B (k2/Ki = 1.0 x 104 M-1sec-1), cathepsin L (k2/Ki = 1.5 x 105 M-1sec-1), cathepsin S (k2/Ki = 6.6 x 104 M-1sec-1), and papain (k2/Ki = 1.0 x 103 M-1sec-1). Half-life in buffered solution (pH 5-9) = 37 h (30°C); 300 h (0°C).
      FormWhite solid
      Chemical formulaC₂₇H₂₇N₃O₇
      Peptide SequenceZ-Phe-Gly-NHO-Bz-pOMe
      Structure formulaStructure formula
      Purity>90% by HPLC
      SolubilityDMSO (5 mg/ml) or Ethanol (1 mg/ml)
      Storage Protect from moisture
      Protect from light
      +15°C to +30°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesDemuth, H.-U., et al. 1996. Biochim. Biophys. Acta 1295, 179.
      Brömme, D., and Demuth, H.-U. 1994. Methods Enzymol. 244, 671.