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219372 Sigma-AldrichCathepsin G Inhibitor I - CAS 429676-93-7 - Calbiochem

Cathepsin G Inhibitor I, CAS 429676-93-7, is a potent, selective, reversible, competitive, non-peptide inhibitor of cathepsin G (IC50 = 53 nM and Ki = 63 nM).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

Primary Target: cathepsin G

Recommended Products

概述

Replacement Information

重要规格表

CAS #	Empirical Formula
429676-93-7	C₃₆H₃₃N₂O₆P

价格及供货情况

产品目录编号	库存情况	包装	数量 / 包装	价格	数量
219372-1MGCN	正在查询供货情况...... — 目前缺货有货停产少量现货供货情况有待确认登录查看库存有货目前缺货有货其余：另行通知其余：另行通知另行通知联系客户服务 Contact Customer Service 联系客户服务联系客户服务	塑胶安瓿;塑胶针药瓶	1 mg	正在检索价格...... 无法检索价格。最小订购数量为倍数 Maximum Quantity is 以订单确认为准更多信息您节约了 ()。 — Request Pricing 登录查看价格	查看库存情况 —	添加到收藏夹添加到收藏夹添加到我的收藏夹
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Description
Overview	A potent, selective, reversible, competitive, non-peptide inhibitor of cathepsin G [IC₅₀ = 53 nM and K_i = 63 nM]. Weakly inhibits chymotrypsin (K_i = 1.5 µM) and poorly inhibits thrombin, factor Xa, factor IXa, plasmin, trypsin, tryptase, proteinase 3, and human leukocyte elastase (IC₅₀ > 100 µM).
Catalogue Number	219372
Brand Family	Calbiochem®

References
References	Greco, M.N., et al. 2002. J. Am. Chem. Soc. 124, 3810.

Product Information
CAS number	429676-93-7
ATP Competitive	N
Form	White solid
Hill Formula	C₃₆H₃₃N₂O₆P
Chemical formula	C₃₆H₃₃N₂O₆P
Reversible	Y
Structure formula Image
Quality Level	MQ100

Applications
Application	Cathepsin G Inhibitor I, CAS 429676-93-7, is a potent, selective, reversible, competitive, non-peptide inhibitor of cathepsin G (IC50 = 53 nM and Ki = 63 nM).

Biological Information
Primary Target	cathepsin G
Primary Target IC<sub>50</sub>	53 nM
Primary Target K<sub>i</sub>	63 nM for cathepsin G
Purity	≥98% by HPLC

Physicochemical Information
Cell permeable	N

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Protect from Light	Protect from light
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
219372-1MGCN	04055977202267
219372-5MGCN	04055977202274

Documentation

Cathepsin G Inhibitor I - CAS 429676-93-7 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

Cathepsin G Inhibitor I - CAS 429676-93-7 - Calbiochem 分析证书

标题	批号
219372	输入批号

参考

参考信息概述
Greco, M.N., et al. 2002. J. Am. Chem. Soc. 124, 3810.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	05-April-2011 RFH
Description	A potent, selective, reversible, and competitive non-peptide inhibitor of cathepsin G (IC₅₀ = 53 nM and K_i = 63 nM). Weakly inhibits chymotrypsin (K_i = 1.5 µM) and does not have any significant inhibitory effect on thrombin, factor Xa, factor IXa, plasmin, trypsin, tryptase, proteinase 3, and human leukocyte elastase (IC₅₀ > 100 µM).
Form	White solid
Intert gas (Yes/No)	Packaged under inert gas
CAS number	429676-93-7
Chemical formula	C₃₆H₃₃N₂O₆P
Structure formula
Purity	≥98% by HPLC
Solubility	DMSO (5 mg/ml) or Methanol
Storage	Protect from light -20°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity	Standard Handling
References	Greco, M.N., et al. 2002. J. Am. Chem. Soc. 124, 3810.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Proteases Inhibitors

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