Custom Premix Selecting "Custom Premix" option means that all of the beads you have chosen will be premixed in manufacturing before the kit is sent to you.
Millipore’s Caspase Antibodies, proteins, and assays have been well validated and published. See below for a comprehensive list of our Caspase products, based on the expertise of Upstate & Chemicon.更多
Millipore’s Caspase Antibodies, proteins, and assays have been well validated and published. See below for a comprehensive list of our Caspase products, based on the expertise of Upstate & Chemicon. 更少
C102144Millipore’s Caspase Antibodies, proteins, and assays have been well validated and published. See below for a comprehensive list of our Caspase products, based on the expertise of Upstate & Chemicon.
Caspases are a family of cytosolic aspartate-specific cysteine proteases involved in the initiation and execution of apoptosis. Caspase 6 is a major apoptotic executioner. It exists as a pro-domain protein and is cleaved by caspase-3 into two subunits, an 18 kDa and a 10 kDa subunit that dimerize to form the active enzyme. Caspase 6 cleaves among many different intracellular proteins, nuclear lamins. Lamins play a significant role in maintaining the integrity of the cell membrane, and their cleavage results in subsequent cellular breakdown and death. EMD Millipore’s Caspase Antibodies, proteins and assays are based on the expertise of Upstate & Chemicon. All have been well validated and published. See the ordering tab for a comprehensive list of our Caspase products and direct links to their technical pages for data, references and related products.
