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			96-Well Plate

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	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

688225 Sigma-AldrichCaspase-1 Substrate VI, Fluorogenic - CAS 219137-85-6 - Calbiochem

Fluorogenic caspase-1 substrate.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
小册子
Data Sheet

同义词: Z-YVAD-AFC

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概述

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Description
Overview	Fluorogenic caspase-1 substrate. Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore.
Catalogue Number	688225
Brand Family	Calbiochem®
Synonyms	Z-YVAD-AFC

References
References	Jones, R.A., et al. 1998. Hepatology 27, 1632. Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312. Walker, N.P., et al. 1994. Cell 78, 343. Thornberry, N.A., et al. 1992. Nature 356, 768.

Product Information
CAS number	219137-85-6
ATP Competitive	N
Form	White to off-white solid
Hill Formula	C₃₃H₃₆F₃N₅O₁₀
Chemical formula	C₃₃H₃₆F₃N₅O₁₀
Reversible	N
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Primary Target	Fluorogenic caspase-1 substrate
Purity	98±1% by HPLC

Physicochemical Information
Cell permeable	N
Emission max.
Excitation max.
Peptide Sequence	Ac-Tyr-Val-Ala-Asp-AFC

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Protect from Light	Protect from light
Protect from Moisture	Protect from moisture
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
688225-5MGCN	04055977225488

Documentation

Caspase-1 Substrate VI, Fluorogenic - CAS 219137-85-6 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

Caspase-1 Substrate VI, Fluorogenic - CAS 219137-85-6 - Calbiochem 分析证书

标题	批号
688225	输入批号

参考

参考信息概述
Jones, R.A., et al. 1998. Hepatology 27, 1632. Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312. Walker, N.P., et al. 1994. Cell 78, 343. Thornberry, N.A., et al. 1992. Nature 356, 768.

小册子

标题
Caspases and other Apoptosis Related Tools Brochure

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	04-April-2011 RFH
Synonyms	Z-YVAD-AFC
Description	Fluorogenic ICE substrate. Reaction can be monitored by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore. AFC (7-amino-4-trifluoromethylcoumarin) based fluorometric substrates are superior to AMC (7-amino-4-methylcoumarin) substrates because released AFC has a greater Stoke's shift than AMC. Excitation/emission maxima (nm) for AFC and AMC are 400/505 and 380/460, respectively.
Form	White to off-white solid
CAS number	219137-85-6
Chemical formula	C₃₃H₃₆F₃N₅O₁₀
Peptide Sequence	Ac-Tyr-Val-Ala-Asp-AFC
Structure formula
Purity	98±1% by HPLC
Solubility	DMSO (5 mg/ml)
Storage	Protect from moisture Protect from light -20°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity	Standard Handling
References	Jones, R.A., et al. 1998. Hepatology 27, 1632. Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312. Walker, N.P., et al. 1994. Cell 78, 343. Thornberry, N.A., et al. 1992. Nature 356, 768.

种类

Life Science Research > Inhibitors and Biochemicals

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