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			96-Well Plate

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	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

208772 Sigma-AldrichCalpain-1 Substrate II, Fluorogenic - Calbiochem

An internally quenched peptide substrate that is optimized for calpain-1 amino acid recognition motifs at the primed as well as the non-primed sides.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

同义词: H-E(EDANS)PLF~AERK(DABCYL)-OH

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概述

Replacement Information

价格及供货情况

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Description
Overview	An internally quenched peptide substrate that is optimized for calpain-1 amino acid recognition motifs at the primed as well as the non-primed sides. Shown to be kinetically superior, in terms of turnover rate, to Calpain Substrate III, Fluorogenic (Cat. No. 208771), Calpain-1 Substrate, Fluorogenic (Cat. No. 208748), and Calpain Substrate II, Fluorogenic (Cat. No. 208731) by ~8-, 18-, and 310-fold, respectively.
Catalogue Number	208772
Brand Family	Calbiochem®
Synonyms	H-E(EDANS)PLF~AERK(DABCYL)-OH

References
References	Cuerrier, D., et al. 2007. J. Biol. Chem. 282, 9600. Cuerrier, D., et al. 2005. J. Biol. Chem. 280, 40632.

Product Information
ATP Competitive	N
Form	Red lyophilized solid
Formulation	Supplied as a trifluoroacetate salt.
Hill Formula	C₇₂H₉₇N₁₇O₁₆S
Chemical formula	C₇₂H₉₇N₁₇O₁₆S
Hygroscopic	Hygroscopic
Reversible	N
Quality Level	MQ100

Applications

Biological Information
Primary Target	Calpain-1 Substrate
Purity	≥97% by HPLC

Physicochemical Information
Cell permeable	N
Emission max.
Excitation max.
Peptide Sequence	H₂N-Glu(EDANS)-Pro-Leu-Phe~Ala-Glu-Arg-Lys(DABCYL)-CO₂H

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Shipped with Blue Ice or with Dry Ice
Toxicity	Irritant
Storage	-20°C
Protect from Light	Protect from light
Hygroscopic	Hygroscopic
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
208772-1MGCN	04055977202861

Documentation

Calpain-1 Substrate II, Fluorogenic - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

Calpain-1 Substrate II, Fluorogenic - Calbiochem 分析证书

标题	批号
208772	输入批号

参考

参考信息概述
Cuerrier, D., et al. 2007. J. Biol. Chem. 282, 9600. Cuerrier, D., et al. 2005. J. Biol. Chem. 280, 40632.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	31-January-2008 JSW
Synonyms	H-E(EDANS)PLF~AERK(DABCYL)-OH
Description	An internally quenched peptide substrate that is optimized for calpain-1 amino acid recognition motifs at the primed as well as the non-primed sides. Shown to be kinetically superior, in terms of turnover rate, to Calpain Substrate III, Fluorogenic (Cat. No. 208771), Calpain-1 Substrate, Fluorogenic (Cat. No. 208748), and Calpain Substrate II, Fluorogenic (Cat. No. 208731) by ~8-, 18-, and 310-fold, respectively. Excitation: ~335 nm; emission: ~505 nm.
Form	Red lyophilized solid
Formulation	Supplied as a trifluoroacetate salt.
Intert gas (Yes/No)	Packaged under inert gas
Chemical formula	C₇₂H₉₇N₁₇O₁₆S
Peptide Sequence	H₂N-Glu(EDANS)-Pro-Leu-Phe~Ala-Glu-Arg-Lys(DABCYL)-CO₂H
Purity	≥97% by HPLC
Solubility	DMSO (5 mg/ml)
Storage	Protect from light -20°C Hygroscopic
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity	Irritant
References	Cuerrier, D., et al. 2007. J. Biol. Chem. 282, 9600. Cuerrier, D., et al. 2005. J. Biol. Chem. 280, 40632.

种类

Life Science Research > Inhibitors and Biochemicals

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