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504761 Sigma-AldrichCL316243 Hydrate - CAS 138908-40-4 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

参考
Data Sheet

同义词: Disodium 5-[(2R)-2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate hydrate

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概述

Replacement Information

重要规格表

CAS #	Empirical Formula
138908-40-4	C₂₀H₁₈ClNNa₂O₇ • H₂O

价格及供货情况

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Description
Overview	A very potent agonist highly selective for β₃ adrenoceptors (EC₅₀ = 3 nM). Widely used to assess the functional roles of β₃ adrenoceptors in glucose homeostasis, thermogenesis, obesity, cardiac functions, retinal neurotoxicity, and tissue inflammation.
Catalogue Number	504761
Brand Family	Calbiochem®
Synonyms	Disodium 5-[(2R)-2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate hydrate

References
References	Flach, R., et al. 2013. Am. J. Pathol. 182, 886. Ghorbani, M., et al. 2012. PloS One 7.10, e45874. Oikawa, F., et al. 2012. Naunyn Schmiedebergs Arch. Pharmacol. 385, 1077. Yoshida, T., et al. 1994. Life Sci. 54, 491. Bloom, J. et al. 1992. J. Med. Chem. 35, 3081.

Product Information
CAS number	138908-40-4
Form	Light beige powder
Hill Formula	C₂₀H₁₈ClNNa₂O₇ • H₂O
Chemical formula	C₂₀H₁₈ClNNa₂O₇ • H₂O
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Primary Target	→₃ adrenoceptors
Purity	≥98% by HPLC

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity	Standard Handling
Storage	+2°C to +8°C
Protect from Light	Protect from light
Do not freeze	Ok to freeze

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
5.04761.0001	04055977244106

Documentation

参考

参考信息概述
Flach, R., et al. 2013. Am. J. Pathol. 182, 886. Ghorbani, M., et al. 2012. PloS One 7.10, e45874. Oikawa, F., et al. 2012. Naunyn Schmiedebergs Arch. Pharmacol. 385, 1077. Yoshida, T., et al. 1994. Life Sci. 54, 491. Bloom, J. et al. 1992. J. Med. Chem. 35, 3081.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	31-May-2013 JSW
Synonyms	Disodium 5-[(2R)-2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate hydrate
Description	A very potent agonist highly selective for ?₃ adrenoceptors (EC50 = 3 nM). Widely used to assess the functional roles of ?₃ adrenoceptors in glucose homeostasis, thermogenesis, obesity, cardiac functions, retinal neurotoxicity, and tissue inflammation.
Form	Light beige powder
CAS number	138908-40-4
Chemical formula	C₂₀H₁₈ClNNa₂O₇ • H₂O
Structure formula
Purity	≥98% by HPLC
Storage	Protect from light +2°C to +8°C
Do Not Freeze	Ok to freeze
Toxicity	Standard Handling
References	Flach, R., et al. 2013. Am. J. Pathol. 182, 886. Ghorbani, M., et al. 2012. PloS One 7.10, e45874. Oikawa, F., et al. 2012. Naunyn Schmiedebergs Arch. Pharmacol. 385, 1077. Yoshida, T., et al. 1994. Life Sci. 54, 491. Bloom, J. et al. 1992. J. Med. Chem. 35, 3081.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Neurochemicals > Agonists > Adrenergic Receptor Agonists

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