Custom Premix Selecting "Custom Premix" option means that all of the beads you have chosen will be premixed in manufacturing before the kit is sent to you.
A selective inhibitor of MMP-13 (IC50 = 10 µM). Binds to the S1′ pocket of MMP-13 with its morpholine ring adjacent to the catalytic zinc atom. Does not inhibit MMP-1, MMP-9, and TACE.
Catalogue Number
233105
Brand Family
Calbiochem®
References
References
Chen, J.M., et al. 2000. J. Am. Chem. Soc.122, 9648.
Chen, J.M., et al. 2000. J. Am. Chem. Soc.122, 9648.
数据表
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
05-April-2011 RFH
Description
A selective inhibitor of MMP-13 (IC50 = 10 µM) that does not appear to act by chelating Zn2+. Binds within the entire S1' pocket of MMP-13, docking with the morpholine ring adjacent to the catalytic zinc atom. Does not inhibit MMP-1, MMP-9, and TACE.
Form
Light yellow solid
CAS number
1188890-36-9
Chemical formula
C₁₇H₂₂N₂O₃· HCl
Structure formula
Purity
≥97% by HPLC
Solubility
H₂O (25 mg/ml)
Storage
-20°C
Hygroscopic
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
Toxicity
Standard Handling
References
Chen, J.M., et al. 2000. J. Am. Chem. Soc.122, 9648.
