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			96-Well Plate

数量	产品目录编号	订购说明	数量 / 包装	公开价
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

211200 Sigma-AldrichCAPE - CAS 104594-70-9 - Calbiochem

A cell-permeable active component of propolis from honeybee hives.

CAPE - CAS 104594-70-9 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

同义词: Caffeic Acid Phenethyl Ester, Synthetic

Primary Target: HIV-integrase

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概述

Replacement Information

重要规格表

CAS #	Empirical Formula
104594-70-9	C₁₇H₁₆O₄

价格及供货情况

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Description
Overview	A cell-permeable active component of propolis from honeybee hives. Known to have antiviral, anti-inflammatory, and immunomodulatory properties. Has also recently been shown to act as a potent and specific inhibitor of NF-κB activation. An inhibitor of HIV-1 integrase activity. Inhibits the growth of different types of transformed cells. Has been reported to suppress lipid peroxidation. Inhibits ornithine decarboxylase, protein tyrosine kinase (PTK), and lipoxygenase activities. Also induces apoptosis in cloned rat embryo fibroblast (CREF) cells transformed by a number of different oncogenes.
Catalogue Number	211200
Brand Family	Calbiochem®
Synonyms	Caffeic Acid Phenethyl Ester, Synthetic

References
References	Nicklaus, M.C., et al. 1997. J. Med. Chem. 40, 920. Natarajan, K., et al. 1996. Proc. Natl. Acad. Sci. USA 93, 9090. Burke, T.R., Jr., et al. 1995. J. Med. Chem. 38, 4171. Laranjinha, J., et al. 1995. Arch. Biochem. Biophys. 323, 373. Su, Z.-Z., et al. 1995. Anticancer Res. 15, 1841. Zheng, Z.S., et al. 1995. Oncol. Res. 7, 445. Su, Z.-Z., et al. 1994. Cancer Res. 54, 1865. Fesen, M.R., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 2399. Guarini, L., et al. 1992. Cell. Mol. Biol. 38, 513.

References

Nicklaus, M.C., et al. 1997. J. Med. Chem. 40, 920.
Natarajan, K., et al. 1996. Proc. Natl. Acad. Sci. USA 93, 9090.
Burke, T.R., Jr., et al. 1995. J. Med. Chem. 38, 4171.
Laranjinha, J., et al. 1995. Arch. Biochem. Biophys. 323, 373.
Su, Z.-Z., et al. 1995. Anticancer Res. 15, 1841.
Zheng, Z.S., et al. 1995. Oncol. Res. 7, 445.
Su, Z.-Z., et al. 1994. Cancer Res. 54, 1865.
Fesen, M.R., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 2399.
Guarini, L., et al. 1992. Cell. Mol. Biol. 38, 513.

Product Information
CAS number	104594-70-9
ATP Competitive	N
Form	White to off-white solid
Hill Formula	C₁₇H₁₆O₄
Chemical formula	C₁₇H₁₆O₄
Reversible	N
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Primary Target	HIV-integrase
Purity	≥97% by HPLC

Physicochemical Information
Cell permeable	Y

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information
R Phrase	R: 36/37/38 Irritating to eyes, respiratory system and skin.
S Phrase	S: 26-36 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing.

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Irritant
Storage	-20°C
Protect from Light	Protect from light
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
211200-25MGCN	07790788048525

Documentation

CAPE - CAS 104594-70-9 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

CAPE - CAS 104594-70-9 - Calbiochem 分析证书

标题	批号
211200	输入批号

参考

参考信息概述
Nicklaus, M.C., et al. 1997. J. Med. Chem. 40, 920. Natarajan, K., et al. 1996. Proc. Natl. Acad. Sci. USA 93, 9090. Burke, T.R., Jr., et al. 1995. J. Med. Chem. 38, 4171. Laranjinha, J., et al. 1995. Arch. Biochem. Biophys. 323, 373. Su, Z.-Z., et al. 1995. Anticancer Res. 15, 1841. Zheng, Z.S., et al. 1995. Oncol. Res. 7, 445. Su, Z.-Z., et al. 1994. Cancer Res. 54, 1865. Fesen, M.R., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 2399. Guarini, L., et al. 1992. Cell. Mol. Biol. 38, 513.

参考信息概述

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	28-May-2008 RFH
Synonyms	Caffeic Acid Phenethyl Ester, Synthetic
Description	A cell-permeable active component of propolis from honeybee hives. Known to have antiviral, anti-inflammatory, and immunomodulatory properties. An inhibitor of HIV-1 integrase activity. Inhibits the growth of different types of transformed cells. Has been reported to suppress lipid peroxidation. Inhibits ornithine decarboxylase, protein tyrosine kinase (PTK) and lipoxygenase activities. Also induces apoptosis in cloned rat embryo fibroblast (CREF) cells transformed by a number of different oncogenes. Has also recently been shown to act as a potent and specific inhibitor of NF-κB activation.
Form	White to off-white solid
Intert gas (Yes/No)	Packaged under inert gas
CAS number	104594-70-9
Chemical formula	C₁₇H₁₆O₄
Structure formula
Purity	≥97% by HPLC
Solubility	DMSO (200 mg/ml) and Ethanol (50 mg/ml)
Storage	Protect from light -20°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
Toxicity	Irritant
References	Nicklaus, M.C., et al. 1997. J. Med. Chem. 40, 920. Natarajan, K., et al. 1996. Proc. Natl. Acad. Sci. USA 93, 9090. Burke, T.R., Jr., et al. 1995. J. Med. Chem. 38, 4171. Laranjinha, J., et al. 1995. Arch. Biochem. Biophys. 323, 373. Su, Z.-Z., et al. 1995. Anticancer Res. 15, 1841. Zheng, Z.S., et al. 1995. Oncol. Res. 7, 445. Su, Z.-Z., et al. 1994. Cancer Res. 54, 1865. Fesen, M.R., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 2399. Guarini, L., et al. 1992. Cell. Mol. Biol. 38, 513.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > NF-κB Activation

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