196810 Sigma-AldrichBax-Inhibiting Peptide, V5 - Calbiochem
Bax-Inhibiting Peptide, V5, CAS 579492-81-2, is a cell-permeable pentapeptide based on the Ku70-Bax inhibiting domain. Acts as an effective Inhibitor for Bax-mediated apoptosis (~50-200 µM).
More>> Bax-Inhibiting Peptide, V5, CAS 579492-81-2, is a cell-permeable pentapeptide based on the Ku70-Bax inhibiting domain. Acts as an effective Inhibitor for Bax-mediated apoptosis (~50-200 µM). Less<<Bax-Inhibiting Peptide, V5 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
同义词: BIP-V5, H-VPMLK-OH
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概述
| Replacement Information |
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重要规格表
| Empirical Formula |
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| C₂₇H₅₀N₆O₆S |
价格及供货情况
| 产品目录编号 | 库存情况 | 包装 | 数量 / 包装 | 价格 | 数量 | |
|---|---|---|---|---|---|---|
| 196810-5MGCN |
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塑胶安瓿;塑胶针药瓶 | 5 mg |
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| Description | |
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| Overview | A cell-permeable pentapeptide based on the Ku70-Bax inhibiting domain that offers cytoprotection. Functions as effectively as the Caspase Inhibitor VI (Z-VAD-FMK; Cat. No. 219007) for Bax-mediated apoptosis (~50-200 µM). Also effectively blocks caspase-independent necrotic cell death. Shown to be Ku70 competitive, interact with Bax, prevent its conformational change and mitochondrial translocation. Displays extended stability in culture medium (~3 days). Negative control peptide is also available (Cat. No. 196811). |
| Catalogue Number | 196810 |
| Brand Family | Calbiochem® |
| Synonyms | BIP-V5, H-VPMLK-OH |
| References | |
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| References | Yoshida, T., et al. 2004. Biochem. Biophys. Res. Commun. 321, 961. Sawada, M., et al. 2003. Nature Cell Biol. 5, 352. |
| Product Information | |
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| ATP Competitive | N |
| Form | White lyophilized solid |
| Formulation | Supplied as a trifluoroacetate salt. |
| Hill Formula | C₂₇H₅₀N₆O₆S |
| Chemical formula | C₂₇H₅₀N₆O₆S |
| Hygroscopic | Hygroscopic |
| Reversible | N |
| Quality Level | MQ100 |
| Biological Information | |
|---|---|
| Primary Target | Bax mediated apoptosis |
| Primary Target IC<sub>50</sub> | 50-200 µM against Bax mediated apoptosis |
| Purity | ≥95% by HPLC |
| Physicochemical Information | |
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| Cell permeable | Y |
| Peptide Sequence | H-Val-Pro-Met-Leu-Lys-OH |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Safety Information |
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| Product Usage Statements |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
| Transport Information |
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| Supplemental Information |
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| Specifications |
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| Global Trade Item Number | |
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| 产品目录编号 | GTIN |
| 196810-5MGCN | 04055977206548 |
Documentation
Bax-Inhibiting Peptide, V5 - Calbiochem MSDS
| 职位 |
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Bax-Inhibiting Peptide, V5 - Calbiochem 分析证书
| 标题 | 批号 |
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| 196810 |
参考
| 参考信息概述 |
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| Yoshida, T., et al. 2004. Biochem. Biophys. Res. Commun. 321, 961. Sawada, M., et al. 2003. Nature Cell Biol. 5, 352. |
小册子
| 标题 |
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| Caspases and other Apoptosis Related Tools Brochure |