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N-cis-2,6-Dimethylpiperidinocarbonyl-L-γ-MeLeu-D-Trp(MeOCO)-D-Nle-OH, Na
References
References
Okada, M., and Nishikibe, M. 2002. Cardiovasc. Drug Reviews20, 53. Taniai, H., et al. 2001. Hepatology33, 894. Fukuroda, T., et al. 1994. Biochem. Biophys. Res. Commun.199, 1461. Ishikawa, K., et al. 1994. Proc. Natl. Acad. Sci. USA91, 4892.
Okada, M., and Nishikibe, M. 2002. Cardiovasc. Drug Reviews20, 53. Taniai, H., et al. 2001. Hepatology33, 894. Fukuroda, T., et al. 1994. Biochem. Biophys. Res. Commun.199, 1461. Ishikawa, K., et al. 1994. Proc. Natl. Acad. Sci. USA91, 4892.
数据表
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
18-September-2008 RFH
Synonyms
N-cis-2,6-Dimethylpiperidinocarbonyl-L-γ-MeLeu-D-Trp(MeOCO)-D-Nle-OH, Na
Description
A highly selective and competitive ETB receptor antagonist (IC50 = 1.2 nM).
Following reconstitution, aliquot and freeze (-20°C). DMSO and Methano:H₂O stock solutions are stable for up to 2 months at -20°C.
Toxicity
Standard Handling
References
Okada, M., and Nishikibe, M. 2002. Cardiovasc. Drug Reviews20, 53. Taniai, H., et al. 2001. Hepatology33, 894. Fukuroda, T., et al. 1994. Biochem. Biophys. Res. Commun.199, 1461. Ishikawa, K., et al. 1994. Proc. Natl. Acad. Sci. USA91, 4892.