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189513 Sigma-AldrichAutotaxin Inhibitor IV, HA155 - CAS 1312201-00-5 - Calbiochem

The Autotaxin Inhibitor IV, HA155 controls the biological activity of Autotaxin. This small molecule/inhibitor is primarily used for Cell Structure applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
参考
Data Sheet

同义词: Atx Inhibitor IV, HA155, (Z)-4-((4-((3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan-5-yliden)-methyl)phenoxy)methyl)benzeneboronic acid

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概述

Replacement Information

重要规格表

CAS #	Empirical Formula
1312201-00-5	C₂₄H₁₉BFNO₅S

价格及供货情况

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Description
Overview	A ~5-fold more potent (IC₅₀ = 5.7 nM) para-isomer boronate analog of Autotaxin Inhibitor II, HA130 (Cat. No. 189511) that efficiently blocks thrombin-stimulated lysophosphatidic acid secretion in platelets and in mammalian cells.
Catalogue Number	189513
Brand Family	Calbiochem®
Synonyms	Atx Inhibitor IV, HA155, (Z)-4-((4-((3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan-5-yliden)-methyl)phenoxy)methyl)benzeneboronic acid

References
References	Fulkerson, Z., et al. 2011. J. Biol. Chem. 286, 34654. Hausmann, J., et al. 2011. Nat. Struct. Mol. Biol. 18, 198. Albers, H.M.H.G., et al. 2011. J. Med. Chem. 54, 4619. Albers, H.M.H.G., et al. 2010. J. Med. Chem. 53, 4958.

Product Information
CAS number	1312201-00-5
Form	Yellow powder
Hill Formula	C₂₄H₁₉BFNO₅S
Chemical formula	C₂₄H₁₉BFNO₅S
Hygroscopic	Hygroscopic
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Purity	≥99% by HPLC

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity	Standard Handling
Storage	-20°C
Protect from Light	Protect from light
Hygroscopic	Hygroscopic
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
189513-10MGCN	04055977221893

Documentation

Autotaxin Inhibitor IV, HA155 - CAS 1312201-00-5 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

参考

参考信息概述
Fulkerson, Z., et al. 2011. J. Biol. Chem. 286, 34654. Hausmann, J., et al. 2011. Nat. Struct. Mol. Biol. 18, 198. Albers, H.M.H.G., et al. 2011. J. Med. Chem. 54, 4619. Albers, H.M.H.G., et al. 2010. J. Med. Chem. 53, 4958.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	30-November-2012 JSW
Synonyms	Atx Inhibitor IV, HA155, (Z)-4-((4-((3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan-5-yliden)-methyl)phenoxy)methyl)benzeneboronic acid
Description	A ~5-fold more potent (IC₅₀ = 5.7 nM) para-isomer boronate analog of Autotaxin Inhibitor II, HA130 (Cat. No. 189511) that efficiently blocks thrombin-stimulated lysophosphatidic acid secretion in platelets and in mammalian cells.
Form	Yellow powder
Intert gas (Yes/No)	Packaged under inert gas
CAS number	1312201-00-5
Chemical formula	C₂₄H₁₉BFNO₅S
Structure formula
Purity	≥99% by HPLC
Solubility	DMSO (100 mg/ml)
Storage	Protect from light -20°C Hygroscopic
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity	Standard Handling
References	Fulkerson, Z., et al. 2011. J. Biol. Chem. 286, 34654. Hausmann, J., et al. 2011. Nat. Struct. Mol. Biol. 18, 198. Albers, H.M.H.G., et al. 2011. J. Med. Chem. 54, 4619. Albers, H.M.H.G., et al. 2010. J. Med. Chem. 53, 4958.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Lipid Signaling Inhibitors > Phospholipase Inhibitors

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