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182540 Sigma-AldrichAromatase Inhibitor I - CAS 331684-05-0 - Calbiochem

The Aromatase Inhibitor I, also referenced under CAS 331684-05-0, controls the biological activity of Aromatase.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

同义词: 4-(Imidazolylmethyl)-1-nitro-9H-9-xanthenone

Primary Target: P450 arom.

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概述

Replacement Information

重要规格表

CAS #	Empirical Formula
331684-05-0	C₁₇H₁₁N₃O₄

价格及供货情况

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Description
Overview	A potent, competitive, nonsteroidal inhibitor of aromatase (P450arom; IC₅₀ = 40 nM for human aromatase). Reported to be more potent than fadrozole in inhibiting aromatase activity. Does not significantly inhibit 17α-hydroxylase.
Catalogue Number	182540
Brand Family	Calbiochem®
Synonyms	4-(Imidazolylmethyl)-1-nitro-9H-9-xanthenone

References
References	Recanatini, M., et al. 2001. J. Med. Chem. 44, 672.

Product Information
CAS number	331684-05-0
ATP Competitive	Y
Form	White solid
Hill Formula	C₁₇H₁₁N₃O₄
Chemical formula	C₁₇H₁₁N₃O₄
Reversible	N
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Primary Target	P450 arom.
Primary Target IC<sub>50</sub>	40 nM against P450arom
Purity	≥95% by HPLC

Physicochemical Information
Cell permeable	N

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Protect from Light	Protect from light
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
182540-1MGCN	04055977205091

Documentation

Aromatase Inhibitor I - CAS 331684-05-0 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

Aromatase Inhibitor I - CAS 331684-05-0 - Calbiochem 分析证书

标题	批号
182540	输入批号

参考

参考信息概述
Recanatini, M., et al. 2001. J. Med. Chem. 44, 672.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	05-April-2011 RFH
Synonyms	4-(Imidazolylmethyl)-1-nitro-9H-9-xanthenone
Description	A potent, selective, nonsteroidal, competitive inhibitor of aromatase (P450arom) (IC₅₀ = 40 nM for human aromatase) Reported to be more potent than fadrozole in inhibiting aromatase activity. Does not significantly inhibit human 17α-hydroxylase (P450 17) (4% inhibition at 2.5 µM).
Form	White solid
Intert gas (Yes/No)	Packaged under inert gas
CAS number	331684-05-0
Chemical formula	C₁₇H₁₁N₃O₄
Structure formula
Purity	≥95% by HPLC
Solubility	DMSO (25 mg/ml)
Storage	Protect from light -20°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity	Standard Handling
References	Recanatini, M., et al. 2001. J. Med. Chem. 44, 672.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Other Inhibitors of Biological Interest > Aromatase Inhibitors

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