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MAB3729 Anti-c-met Antibody, clone 4AT44

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MAB3729
400 µl  
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      概述

      Replacement Information

      重要规格表

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, MWBMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMAB3729
      Replaces04-1051
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-c-met Antibody, clone 4AT44
      Alternate Names
      • Hepatocyte Growth Factor Receptor
      • HGFR
      References
      Product Information
      FormatPurified
      PresentationProtein G purified immunoglobulin. Liquid in PBS containing 0.09% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-c-met Antibody, clone 4AT44 is validated for use in WB for the detection of c-met.
      Key Applications
      • Western Blotting
      Application NotesWestern Blot: 1:100-1:500.

      ELISA (direct): 1:1,000

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenPurified recombinant catalytic domain of human Met
      Clone4AT44
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityReacts with c-met/HGFR (Hepatocyte growth factor receptor). The Met receptor tyrosine kinase is the prototypical member of a small subfamily of growth factor receptors that when activated, induces mitogenic, motogenic, and morphogenic cellular responses. The ligand for c-met is hepatocyte growth factor/scatter factor (HGF/SF) and while normal HGF/SF-Met signaling is required for embryonic development, abnormal c-met signaling has been strongly implicated in tumorigenesis, particularly in the development of invasive and metastatic phenotypes.
      IsotypeIgG1
      Species Reactivity
      • Human
      • Mouse
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      UniProt Number
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size400 µl
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      产品目录编号 GTIN
      MAB3729 04053252580277

      Documentation

      Anti-c-met Antibody, clone 4AT44 MSDS

      职位

      物料安全数据表 (MSDS) 

      Anti-c-met Antibody, clone 4AT44 分析证书

      标题批号
      Anti-c-met, clone 4AT44 - 3248392 3248392
      Anti-c-met, clone 4AT44 - 3875550 3875550
      Anti-c-met, clone 4AT44 -2554846 2554846
      Anti-c-met, clone 4AT44 -2580687 2580687
      Anti-c-met, clone 4AT44 -2689152 2689152
      Anti-c-met, clone 4AT44 Monoclonal Antibody 3033932
      Anti-c-met, clone 4AT44 Monoclonal Antibody 3131885
      MOUSE ANTI-MET/HGFR MONOCLONAL ANTIBODY - 2120947 2120947
      MOUSE ANTI-MET/HGFR MONOCLONAL ANTIBODY - 2043873 2043873
      MOUSE ANTI-MET/HGFR MONOCLONAL ANTIBODY - 2198940 2198940

      参考

      参考概述公共医疗ID
      Decorin antagonizes Met receptor activity and down-regulates {beta}-catenin and Myc levels.
      Buraschi, S; Pal, N; Tyler-Rubinstein, N; Owens, RT; Neill, T; Iozzo, RV
      The Journal of biological chemistry  285  42075-85  2010

      显示摘要 全文本文章
      20974860 20974860
      A novel multipurpose monoclonal antibody for evaluating human c-Met expression in preclinical and clinical settings.
      Knudsen, BS; Zhao, P; Resau, J; Cottingham, S; Gherardi, E; Xu, E; Berghuis, B; Daugherty, J; Grabinski, T; Toro, J; Giambernardi, T; Skinner, RS; Gross, M; Hudson, E; Kort, E; Lengyel, E; Ventura, A; West, RA; Xie, Q; Hay, R; Vande Woude, G; Cao, B
      Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry  17  57-67  2009

      显示摘要 全文本文章
      18815565 18815565
      Antibody validation by quantitative analysis of protein expression using expression of Met in breast cancer as a model.
      Pozner-Moulis, S; Cregger, M; Camp, RL; Rimm, DL
      Laboratory investigation; a journal of technical methods and pathology  87  251-60  2007

      显示摘要
      17260003 17260003

      数据表

      标题
      MOUSE ANTI-MET/HGFR MONOCLONAL ANTIBODY

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      种类

      Life Science Research > Antibodies and Assays > Primary Antibodies