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	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

MABC110 Sigma-AldrichAnti-WIPI-2, clone 1B8.1 Antibody

This Anti-WIPI-2, clone 1B8.1 Antibody is validated for use in Western Blotting and Immunohistochemistry (Paraffin) for the detection of WIPI-2.

Anti-WIPI-2, clone 1B8.1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书

Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: WIPI2, CGI-50 UniProt Number: Q9Y4P8

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概述

Replacement Information

特卖

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H	WB, IH(P)	M	Purified	Monoclonal Antibody

Description
Catalogue Number	MABC110
Description	Anti-WIPI-2, clone 1B8.1 Antibody
Alternate Names	WD repeat domain phosphoinositide-interacting protein 2 WIPI-2 WIPI49-like protein 2
Background Information	WIPI-2, also known as Atg18, is involved in autophagy by regulating the assembly of mulitprotein complexes by presenting a 7-bladed propeller structure for interactions with phospholipids. Atg18 is a mammalian effector of PtdIns3P and is ubiquitously expressed in a variety of cell lines. Studies show that Atg18 is recruited to early autophagosomal structural formation along with Atg16 and ULK1, and Atg18 is required for the formation of LC3-positive autophagosomes.

References

Product Information
Format	Purified
Presentation	Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level	MQ100

Applications
Application	This Anti-WIPI-2, clone 1B8.1 Antibody is validated for use in Western Blotting and Immunohistochemistry (Paraffin) for the detection of WIPI-2.
Key Applications	Western Blotting Immunohistochemistry (Paraffin)
Application Notes	Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected WIPI-2 in human pancreas tissue.

Biological Information
Immunogen	GST-tagged recombinant protein corresponding to the C-terminus of human WIPI-2.
Epitope	C-terminus
Clone	1B8.1
Concentration	Please refer to lot specific datasheet.
Host	Mouse
Isotype	IgG2aκ
Species Reactivity	Human
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NP_001028690
Gene Symbol	WIPI2 CGI-50
Purification Method	Protein G Purified
UniProt Number	Q9Y4P8
Molecular Weight	~49 kDa observed. Uncharacterized band(s) may appear in some lysates.

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by Western Blotting in human testis tissue lysate. Western Blotting Analysis: 2.0 µg/mL of this antibody detected WIPI-2 in 10 µg of human testis tissue lysate.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at 2-8°C from date of receipt.

Packaging Information
Material Size	100 µg

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
MABC110	04053252996160

Documentation

Anti-WIPI-2, clone 1B8.1 Antibody MSDS

职位
物料安全数据表 (MSDS)

Anti-WIPI-2, clone 1B8.1 Antibody 分析证书

标题	批号
Anti-WIPI-2, clone 1B8.1 - Q2456159	Q2456159

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描述

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种类

Life Science Research > Antibodies and Assays > Primary Antibodies

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