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	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

MABT161 Sigma-AldrichAnti-Versican Antibody, clone 8D8.1

Detect Versican using this mouse monoclonal antibody, Anti-Versican Antibody, clone 8D8.1 validated for use in IHC & western blotting.

Anti-Versican Antibody, clone 8D8.1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书

Research Category: Cell Structure Research Sub-Category: ECM Proteins Gene Symbol: VACN, CSPG2 UniProt Number: P13611

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概述

Replacement Information

特卖

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H, M	IHC, WB	M	Purified	Monoclonal Antibody

Description
Catalogue Number	MABT161
Description	Anti-Versican Antibody, clone 8D8.1
Alternate Names	Versican core protein Chondroitin sulfate proteoglycan core protein 2 Chondroitin sulfate proteoglycan 2 Glial hyaluronate-binding protein GHAP Large fibroblast proteoglycan PG-M
Background Information	Versican is a large multi-domain chondroitin sulphate proteoglycan, is secreted by fibroblasts and other types of cells. It has a N-terminal hyaluronic acid (HA) binding domain. This domain has homology with the G1 and G2 domains of aggrecan, (G1 is the hyaluronic acid binding region), to cartilage link protein which stabilizes the binding of aggrecan to hyaluronic acid, and, to the hyaluronate receptor CD44. In addition, versican also has a lectin like domain, a C-terminal compliment repeat, and two EGF-like repeats, all of which can be found in aggrecan. Versican has an apparent molecular mass of ca. 1000 kDa, of which the core contributes 400 kDa from the 2409 amino acids, and the 12 -15 covalently attached chondroitin sulphate chains make up the rest.

References

Product Information
Format	Purified
Control	Human thalamus tissue lysate
Presentation	Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
Quality Level	MQ100

Applications
Application	Detect Versican using this mouse monoclonal antibody, Anti-Versican Antibody, clone 8D8.1 validated for use in IHC & western blotting.
Key Applications	Immunohistochemistry Western Blotting
Application Notes	Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Versican in human cerebellum, and mouse brain and embryonic skeletal muscle. Western Blotting Analysis: 0.2 µg/mL from a representative lot detected Versican in mouse leg muscle tissue lysate.

Biological Information
Immunogen	KLH-conjugated linear peptide corresponding to the C-terminus of human Veriscan.
Epitope	C-terminus
Clone	8D8.1
Concentration	Please refer to the Certificate of Analysis for the lot-specific concentration.
Host	Mouse
Specificity	This antibody recognizes the C-terminus of Veriscan.
Isotype	IgMκ
Species Reactivity	Human Mouse
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NP_00119808
Gene Symbol	VACN CSPG2
UniProt Number	P13611
Molecular Weight	372 kDa calculated. Uniprot describes three isoforms at 265 kDa, 182 kDa, and 74 kDa. Versican is known to be secreted following valvular interstitual cell (VIC) injury and repair (Carthy, J., et al. (2012). Cardiovac. Pathol. 21(2):74-82.).

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by Immunohistochemistry in human thalamus tissue lysate. Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Versican in human thalamus tissue lysate.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at 2-8°C from date of receipt.

Packaging Information
Material Size	100 µg

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
MABT161	04053252917004

Documentation

Anti-Versican Antibody, clone 8D8.1 MSDS

职位
物料安全数据表 (MSDS)

Anti-Versican Antibody, clone 8D8.1 分析证书

标题	批号
Anti-Versican, clone 8D8.1 - 3249441	3249441
Anti-Versican, clone 8D8.1 - 3305166	3305166
Anti-Versican, clone 8D8.1 - 3386475	3386475
Anti-Versican, clone 8D8.1 - 3928039	3928039
Anti-Versican, clone 8D8.1 - 4133112	4133112
Anti-Versican, clone 8D8.1 - Q2219514	Q2219514
Anti-Versican, clone 8D8.1 -2567745	2567745
Anti-Versican, clone 8D8.1 -2617690	2617690
Anti-Versican, clone 8D8.1 -2649293	2649293
Anti-Versican, clone 8D8.1 -2702191	2702191

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描述

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种类

Life Science Research > Antibodies and Assays > Primary Antibodies

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