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MABT75 Sigma-AldrichAnti-Titin (NT/Z-domain) Antibody, clone 17D11.1

Anti-Titin (N-terminal/Z-domain) Antibody, clone 17D11.1 is an antibody against Titin (N-terminal/Z-domain) for use in Western Blotting, IHC(P).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
小册子

Research Category: Cell Structure Research Sub-Category: Cytoskeleton Gene Symbol: TTN UniProt Number: Q8WZ42

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Replacement Information

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H, M	WB, IH(P)	M	Purified	Monoclonal Antibody

Description
Catalogue Number	MABT75
Description	Anti-Titin (NT/Z-domain) Antibody, clone 17D11.1
Alternate Names	Titin Connectin Rhabdomyosarcoma antigen MU-RMS-40.14
Background Information	Titin is a large complex protein containing over one hundred IgG-like and fibronectin type-III domains, in addition to multiple Kelch, RCC1, TPR, and WD repeats. It is a member of the CAMK Ser/Thr protein kinase family and also possesses a protein kinase domain, which is involved in controlling gene expression and protein turnover in muscle tissues. Titin also functions as a sensor to mediate appropriate cellular responses to mechanical stress. In striated muscle tissue, titin regulates the length of the sarcomere by integrating myosin and actin filaments at the Z-disk and M-band, and facilitates the elasticity of the sarcomere. Titin also regulates sarcomere assembly and functions as central hub in signal transduction pathways. Defects in Titin may contribute to various forms of cardiomyopathy.

References

Product Information
Format	Purified
Control	Human and mouse cardiac muscle tissues
Presentation	Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level	MQ100

Applications
Application	Anti-Titin (N-terminal/Z-domain) Antibody, clone 17D11.1 is an antibody against Titin (N-terminal/Z-domain) for use in Western Blotting, IHC(P).
Key Applications	Western Blotting Immunohistochemistry (Paraffin)

Biological Information
Immunogen	GST-tagged recombinant protein corresponding to human Titin.
Clone	17D11.1
Concentration	Please refer to the Certificate of Analysis for the lot-specific concentration.
Host	Mouse
Isotype	IgG1κ
Species Reactivity	Human Mouse
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NP_596870
Gene Symbol	TTN
Purification Method	Protein G Purified
UniProt Number	Q8WZ42
Molecular Weight	38 kDa calculated

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by Immunohistochemistry in human and mouse cardiac muscle tissues. Immunohistochemistry Analysis: 1:1,000 dilution of this antibody detected Titin in human and mouse cardiac muscle tissues.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at 2-8°C from date of receipt.

Packaging Information
Material Size	100 µg

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
MABT75	04053252646331

Documentation

Anti-Titin (NT/Z-domain) Antibody, clone 17D11.1 MSDS

职位
物料安全数据表 (MSDS)

Anti-Titin (NT/Z-domain) Antibody, clone 17D11.1 分析证书

标题	批号
Anti-Titin (N-terminal/Z-domain), clone 17D11.1 - 2433594	2433594
Anti-Titin (N-terminal/Z-domain), -2724172	2724172
Anti-Titin (N-terminal/Z-domain), -2774076	2774076
Anti-Titin (N-terminal/Z-domain), clone 17D11.1 - 3311782	3311782
Anti-Titin (N-terminal/Z-domain), clone 17D11.1 - 3386473	3386473
Anti-Titin (N-terminal/Z-domain), clone 17D11.1 - 3736709	3736709
Anti-Titin (N-terminal/Z-domain), clone 17D11.1 - 3880435	3880435
Anti-Titin (N-terminal/Z-domain), clone 17D11.1 - 3899582	3899582
Anti-Titin (N-terminal/Z-domain), clone 17D11.1 - Q2015738	Q2015738
Anti-Titin (N-terminal/Z-domain), clone 17D11.1 Monoclonal Antibody	3134088

小册子

标题
New Products: Volume 3, 2012

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描述

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种类

Life Science Research > Antibodies and Assays > Primary Antibodies

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