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MABE430 Sigma-AldrichAnti-TIP60 Antibody, clone 3F9

Anti-TIP60 Antibody, clone 3F9 is a highly specific mouse monoclonal antibody, that targets Tip60 & has been tested in western blotting & IHC.

Anti-TIP60 Antibody, clone 3F9 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书

Research Category: Epigenetics & Nuclear Function Research Sub-Category: Transcription Factors Gene Symbol: TIP60, KAT5, HTATIP UniProt Number: P63279

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概述

Replacement Information

特卖

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H	WB, IHC	M	Ascites	Monoclonal Antibody

Description
Catalogue Number	MABE430
Description	Anti-TIP60 Antibody, clone 3F9
Alternate Names	Histone acetyltransferase KAT5 60 kDa Tat-interactive protein Tip60 Histone acetyltransferase HTATIP HIV-1 Tat interactive protein Lysine acetyltransferase 5 cPLA(2)-interacting protein
Background Information	TIP60 protein or also known as Histone acetyltransferase KAT5, 60kDa Tat-interactive protein, Histone acetyltransferase HTATIP, HIV-1 Tat interactive protein, Lysine acetyltransferase 5, or cPLA(2)-interacting protein and encoded by the KAT5/HTATIP/TIP60 gene is a histone acetyl transferase that forms the catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of a number of genes via the acetylation of histone H4 and H2A. TIP60 plays a role in DNA repair, growth arrest and senescence, apoptosis, chromatin remodeling, and tumor suppression. First discovered as protein that interacted with HIV-1 Tat resulting in TIP60 becoming polyubiquitinated and degraded (which prevented apoptosis of the infected cell), TIP60 is now known to interact with a number of other intracellular proteins including HDAC7A, CREB1, BCL3, Androgen receptor and PLA2G4A. TIP60 is largely localized to the nucleus or nuclear envelope in most tissues. TIP60 is also necessary for oncogene and proto-oncogene mediated growth induction seen in many cancers. EMD-Millipore’s Anti-TIP60 mouse monoclonal antibody has been tested in western blot on recombinant TIP60 protein and in paraffin embedded immunohistochemistry on human liver carcinoma, rectum carcinoma, normal medulla and normal interbrain tissue sections.

References

Product Information
Format	Ascites
Control	Human recombinant TIP60 protein
Presentation	Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
Quality Level	MQ100

Applications
Application	Anti-TIP60 Antibody, clone 3F9 is a highly specific mouse monoclonal antibody, that targets Tip60 & has been tested in western blotting & IHC.
Key Applications	Western Blotting Immunohistochemistry
Application Notes	Immunohistochemistry Analysis: A 1:200-1,000 dilution from a representative lot detected TIP60 in liver carcinoma, rectum carcinoma, normal medulla and interbrain tissues. Optimal working dilutions must be determined by end user.

Biological Information
Immunogen	Purified recombinant fragment of human TIP60 expressed in E. Coli.
Clone	3F9
Host	Mouse
Isotype	IgG2b
Species Reactivity	Human
Antibody Type	Monoclonal Antibody
Gene Symbol	TIP60 KAT5 HTATIP
Purification Method	Unpurified
UniProt Number	P63279
Molecular Weight	~60 kDa observed. Uncharacterized bands may appear in some lysate(s).

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by Western Blotting in human recombinant TIP60 protein. Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected human recombinant TIP60 protein.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Packaging Information
Material Size	100 µL

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
MABE430	04053252920530

Documentation

Anti-TIP60 Antibody, clone 3F9 MSDS

职位
物料安全数据表 (MSDS)

Anti-TIP60 Antibody, clone 3F9 分析证书

标题	批号
Anti-TIP60, clone 3F9 - QVP1306171	QVP1306171
Anti-TIP60, clone 3F9 - VP1912132	VP1912132
Anti-TIP60, clone 3F9 -VP1410075	VP1410075
Anti-TIP60, clone 3F9 -VP1602243	VP1602243
Anti-TIP60, clone 3F9 -VP1604190	VP1604190
Anti-TIP60, clone 3F9 -VP1611236	VP1611236
Anti-TIP60, clone 3F9 Monoclonal Antibody	VP1712292
Anti-TIP60, clone 3F9 Monoclonal Antibody	VP1708213

种类

Life Science Research > Antibodies and Assays > Primary Antibodies

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