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	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

MABN774 Sigma-AldrichAnti-TDP-43 Antibody, clone DB9

Detect TDP-43 using this Anti-TDP-43 Antibody, clone DB9 validated for use in western blotting & IHC.

Anti-TDP-43 Antibody, clone DB9 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书

Research Category: Neuroscience Research Sub-Category: Neurodegenerative Diseases Gene Symbol: TARDBP, TDP43 UniProt Number: Q13148

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概述

Replacement Information

特卖

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H	WB, IHC	M	Purified	Monoclonal Antibody

Description
Catalogue Number	MABN774
Description	Anti-TDP-43 Antibody, clone DB9
Alternate Names	TAR DNA-binding protein 43 TDP-43 TDP43 TAR DNA binding protein-43
Background Information	TAR DNA-binding protein 43 (TDP-43) belongs to the hnRNP protein family and plays an important role in transcription, pre-mRNA splicing, mRNA stability and mRNA transport. It is involved in splicing of the apolipoprotein A-II and cystic fibrosis transmembrane gene. This protein is highly expressed in the pancreas, placenta, lung, genital tract and spleen. Mutations in TDP-43 have been associated with amyotrophic lateral sclerosis, frontotemporal dementia, Parkinson's disease and Alzheimer's disease.

References

Product Information
Format	Purified
Presentation	Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level	MQ100

Applications
Application	Detect TDP-43 using this Anti-TDP-43 Antibody, clone DB9 validated for use in western blotting & IHC.
Key Applications	Western Blotting Immunohistochemistry
Application Notes	Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected TDP-43 in human cerebellum, pancreas, and thalamus tissues.

Biological Information
Immunogen	The antibody was raised against an immunogen consisting of His-tagged recombinant protein corresponding to amino acid residues 208-414 of human TDP-43.
Clone	DB9
Concentration	Please refer to the Certificate of Analysis for the lot-specific concentration.
Host	Mouse
Isotype	IgG1κ
Species Reactivity	Human
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NP_031401
Gene Symbol	TARDBP TDP43
Purification Method	Protein G Purified
UniProt Number	Q13148
Molecular Weight	~43 kDa observed

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by Western Blotting in SH-SY-5Y cell lysate. Western Blotting Analysis: 2 µg/mL of this antibody detected TDP-43 in 10 µg of SH-SY-5Y cell lysate.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at 2-8°C from date of receipt.

Packaging Information
Material Size	100 µg

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
MABN774	04053252946059

Documentation

Anti-TDP-43 Antibody, clone DB9 MSDS

职位
物料安全数据表 (MSDS)

Anti-TDP-43 Antibody, clone DB9 分析证书

标题	批号
Anti-TDP-43, clone DB9 - 3205457	3205457
Anti-TDP-43, clone DB9 - 3483445	3483445
Anti-TDP-43, clone DB9 - 3604765	3604765
Anti-TDP-43, clone DB9 - 3724694	3724694
Anti-TDP-43, clone DB9 - 3839157	3839157
Anti-TDP-43, clone DB9 - 3879502	3879502
Anti-TDP-43, clone DB9 - 4108272	4108272
Anti-TDP-43, clone DB9 - 4163450	4163450
Anti-TDP-43, clone DB9 - Q2364942	Q2364942
Anti-TDP-43, clone DB9 -2796263	2796263

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种类

Life Science Research > Antibodies and Assays > Primary Antibodies

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