数量	产品目录编号	订购说明	数量 / 包装	公开价
			96-Well Plate

数量	产品目录编号	订购说明	数量 / 包装	公开价
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

MABF1214-I Sigma-AldrichAnti-TCL1A Antibody, clone TCL1A

This Anti-TCL1A Antibody, clone TCL1A is validated for use in Western Blotting, Immunocytochemistry for the detection of TCL1A.

Anti-TCL1A Antibody, clone TCL1A MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

分析证书
小册子
Posters

Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology Gene Symbol: TCL1A, TCL1 UniProt Number: P56279

Recommended Products

概述

Replacement Information
Replacement Information	MABF1214-I is the purified version of 05-954 which is also suitable also for Immunohistochemistry application. Alexa 488 conjugated version of this product is also available under MABF1214-AF488.

特卖

100% Performance Guaranteed

重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H	WB, ICC	M	Purified	Monoclonal Antibody

Description
Catalogue Number	MABF1214-I
Description	Anti-TCL1A Antibody, clone TCL1A
Alternate Names	T-cell leukemia/lymphoma protein 1A TCL1A Oncogene TCL-1 Oncogene TCL1 Protein p14 TCL1
Background Information	T-cell leukemia/lymphoma protein 1A (UniProt P56279; also known as Oncogene TCL-1, Oncogene TCL1, Protein p14 TCL1, T-cell lymphoma-1) is encoded by the TCL1A (also known as TCL1) gene (Gene ID 8115) in human. TCL1A belongs to the T-cell leukemia/lymphoma 1 (TCL1) family of oncoproteins that enhance cell proliferation and survival by augmenting AKT signal transduction. TCL1A and the related TCL1B play key roles in several B and T cell malignancies. TCL1A does not exhibit enzymatic activity and functions as an AKT activity enhancer via binding to its pleckstrin homology (PH) domain, resulting in enhanced phosphorylation of downstream AKT substrates, such as glycogen synthase kinase-3 beta (GSK3beta). TCL1A is also reported to interact with IkappaB, albeit as a ~100-fold lower affinity than NF-kappaB.

References

Product Information
Format	Purified
Presentation	Purified mouse monoclonal IgG antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level	MQ100

Applications
Application	This Anti-TCL1A Antibody, clone TCL1A is validated for use in Western Blotting, Immunocytochemistry for the detection of TCL1A.
Key Applications	Western Blotting Immunocytochemistry
Application Notes	Immunocytochemistry Analysis: A 1:200 dilution from a representative lot detected TCL1A in HUVECs.

Biological Information
Immunogen	KLH-conjugated, synthetic peptide corresponding to amino acids 60-73 (RPMTPTQIGPSLLP) of human TCL1A.
Epitope	a.a. 60-73
Clone	TCL1A
Concentration	Please refer to lot specific datasheet.
Host	Mouse
Specificity	TCL1A, no cross-reactivity with TML1 (TCL1B) or MTCP1.
Isotype	IgG
Species Reactivity	Human
Species Reactivity Note	Human. Predicted to react with Non-Human Primate based on 100% sequence homology.
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NP_001092195
Gene Symbol	TCL1A TCL1
Purification Method	Protein G Purified
UniProt Number	P56279
Molecular Weight	~13 kDa observed

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by Western Blotting in Raji cell lysate. Western Blotting Analysis: 0.5 µg/mL of this antibody detected TCL1A in 10 µg of Raji cell lysate.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at 2-8°C from date of receipt.

Packaging Information
Material Size	100 μg

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
MABF1214-I	04055977298321

Documentation

Anti-TCL1A Antibody, clone TCL1A 分析证书

标题	批号
Anti-TCL1A, clone TCL1A -Q2622172	Q2622172

小册子

标题
New Products Flyer- Vol 4 Signaling Feature- NEW! Phosphohistidine Antibody

海报

标题
Post-Translational Modifications

Related Products

产品目录编号

描述

05-954

Anti-TCL1 Antibody

显示价格及库存情况

MABF1214-AF488

Anti-TCL1A Antibody, clone TCL1A, Alexa Fluor® 488 Conjugate

显示价格及库存情况

种类

Life Science Research > Antibodies and Assays > Primary Antibodies

此产品已添加到您的购物车。