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Recognizes the ~43-45 kDa TANK protein in human liver tissue.
Catalogue Number
ST1608
Brand Family
Calbiochem®
Synonyms
Anti-TRAF Associated NF-κB Activator
Application Data
Detection of human TANK by immunoblotting. Sample: Whole tissue extract from human liver. Primary antibody: Anti-TANK Rabbit pAb (Cat. No. ST1608) (1-5 µg/ml). Detection: chemiluminescence.
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
09-November-2010 RFH
Synonyms
Anti-TRAF Associated NF-κB Activator
Application
Immunoblotting (1-5 µg/ml)
Application Data
Detection of human TANK by immunoblotting. Sample: Whole tissue extract from human liver. Primary antibody: Anti-TANK Rabbit pAb (Cat. No. ST1608) (1-5 µg/ml). Detection: chemiluminescence.
Description
Purified rabbit polyclonal antibody. Recognizes the ~43-45 kDa TANK protein.
Background
The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-κB activation. Two transcript variants encoding different isoforms have been found for this gene.
Host
Rabbit
Immunogen species
Human
Immunogen
Full-length, human TANK (aa 1-119)
Isotype
IgG
Species
human
Positive control
Human liver tissue
Form
Liquid
Formulation
In PBS, pH 7.2.
Preservative
None
Comments
Variables associated with assay conditions will dictate the proper working dilution.
Storage
Avoid freeze/thaw
-20°C
Do Not Freeze
Ok to freeze
Special Instructions
Following initial thaw, aliquot and freeze (-20°C).
