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AB5779 Anti-Striatin Antibody

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AB5779
100 µL  
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      概述

      重要规格表

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RIP, WB, ICCRbSerumPolyclonal Antibody
      Description
      Catalogue NumberAB5779
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Striatin Antibody
      Background InformationStriatin is found in all mammalian cells and may be involved in vesicular transport, dendrite growth and cellular signalling. It binds Protein phosphatase 2A (PP2A) A and C subunits and calmodulin and appears to modulate PP2A activity. It also binds the human homolog of the yeast protein, Mob1, which has been implicated in mitotic progression in yeast. It is a member of a family of proteins that also include SG2NA (striatin 3) and Zinedin (striatin 4).
      Product Information
      FormatSerum
      PresentationRabbit serum. Liquid containing 40% glycerol and 0.02% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Striatin Antibody detects level of Striatin & has been published & validated for use in IP, WB & IC.
      Key Applications
      • Immunoprecipitation
      • Western Blotting
      • Immunocytochemistry
      Application NotesWestern blot: 1:500-1:1,000. The antibody reacts with the ~110 kDa striatin protein in 293 cell lysate.

      Immunocytochemistry: 1:500

      Immunoprecitation: 3 μL recommended as starting point.

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenSynthetic Striatin peptide.
      HostRabbit
      SpecificityReacts with Striatin. No cross reactivity with SG2NA.
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • STRN
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: O43815 # Calmodulin-binding protein which may function as scaffolding or signaling protein and may play a role in dendritic Ca(2+) signaling.
      SIZE: 780 amino acids; 86132 Da
      SUBUNIT: Interacts with protein phosphatase 2A (PP2A) (Potential).
      SUBCELLULAR LOCATION: Cytoplasm (By similarity). Membrane; Peripheral membrane protein (By similarity).
      TISSUE SPECIFICITY: Preferentially expressed in brain.
      SIMILARITY: SwissProt: O43815 ## Belongs to the WD repeat striatin family. & Contains 6 WD repeats.
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -20°C in undiluted for up to 12 months after date of receipt. For long-term storage, may be stored at -80°C. Avoid repeated freeze/thaw cycles at temperatures below -20°C.
      Packaging Information
      Material Size100 µL
      Global Trade Item Number
      产品目录编号 GTIN
      AB5779 04053252670381