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MABS178 Sigma-AldrichAnti-STK39 Antibody, clone 5H7.1

Anti-STK39 Antibody, clone 5H7.1 is a highly specific mouse monoclonal antibody, that targets STK39 & has been tested in western blotting & IHC.

Anti-STK39 Antibody, clone 5H7.1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书

Research Category: Signaling Research Sub-Category: Developmental Signaling Gene Symbol: STK39, SPAK UniProt Number: Q9UEW8

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概述

Replacement Information

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H, M, R	WB, IHC	M	Purified	Monoclonal Antibody

Description
Catalogue Number	MABS178
Description	Anti-STK39 Antibody, clone 5H7.1
Alternate Names	STE20/SPS1-related proline-alanine-rich protein kinase Ste-20-related kinase DCHT Serine/threonine-protein kinase 39
Background Information	Serine/threonine-protein kinase 39 (STK39), also known as STE20/SPS-1 related proline alanine-rich kinase (SPAK), is a member of the SPS1 subfamily of STE20 kinases. STK39 is also very highly conserved between species and has been shown to activate the p38 pathways. STK39 also has a caspase cleavage site and these two functions may mean that STK39 plays a role in stress-activated signaling. STK39 expression is up-regulated by androgens in LNCaP human prostate cancer cells and regulated and phosphorylated by WNK1, which controls the stress signaling pathway. It is activated by WNK4 and then has the ability to stimulate the Na-K-2Cl cotransporter, the inactive version does not possess this ability. Recent research has also made a connection between STK39 and regulation of blood pressure.

References

Product Information
Format	Purified
Presentation	Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level	MQ100

Applications
Application	Anti-STK39 Antibody, clone 5H7.1 is a highly specific mouse monoclonal antibody, that targets STK39 & has been tested in western blotting & IHC.
Key Applications	Western Blotting Immunohistochemistry
Application Notes	Western Blotting Analysis: 1.0 µg/mL from a representative lot detected STK39 in 10 µg of mouse and rat brain tissue lysate. Immunohistochemistry Analysis: A 1:500-2,000 dilution from a representative lot detected STK39 in human cerebellum sections and rat hindbrain sections tissue.

Biological Information
Immunogen	GST-tagged recombinant protein corresponding to the C-terminus of human STK39.
Epitope	C-terminus
Clone	5H7.1
Concentration	Please refer to the Certificate of Analysis for the lot-specific concentration.
Host	Mouse
Specificity	This antibody recognizes the C-terminus of STK39.
Isotype	IgG1κ
Species Reactivity	Human Mouse Rat
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NP_037365
Gene Symbol	STK39 SPAK
Purification Method	Protein G Purified
UniProt Number	Q9UEW8
Molecular Weight	~60 kDa observed

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by Western Blotting in human brain tissue lysate. Western Blotting Analysis: 1.0 µg/mL of this antibody detected STK39 in 10 µg of human brain tissue lysate.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at 2-8°C from date of receipt.

Packaging Information
Material Size	100 µg

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
MABS178	04053252927232

Documentation

Anti-STK39 Antibody, clone 5H7.1 MSDS

职位
物料安全数据表 (MSDS)

Anti-STK39 Antibody, clone 5H7.1 分析证书

标题	批号
Anti-STK39, clone 5H7.1 - 3601745	3601745
Anti-STK39, clone 5H7.1 - 3824853	3824853
Anti-STK39, clone 5H7.1 - 4061827	4061827
Anti-STK39, clone 5H7.1 - 4116938	4116938
Anti-STK39, clone 5H7.1 - Q2279648	Q2279648
Anti-STK39, clone 5H7.1 -2894068	2894068
Anti-STK39, clone 5H7.1 Monoclonal Antibody	2933873
Anti-STK39, clone 5H7.1 Monoclonal Antibody	3149918
Anti-STK39, clone 5H7.1 Monoclonal Antibody	2981028

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种类

Life Science Research > Antibodies and Assays > Primary Antibodies

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