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			96-Well Plate

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	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

MABF284 Sigma-AldrichAnti-RIG1 Antibody, clone 42

This Anti-RIG1 Antibody, clone 42 is validated for use in Western Blotting and Flow Cytometry for the detection of RIG1.

Anti-RIG1 Antibody, clone 42 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书

Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology Gene Symbol: RARRES3, RIG1, TIG3 UniProt Number: Q9UL19

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概述

Replacement Information

特卖

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H	WB, FC	M	Purified	Monoclonal Antibody

Description
Catalogue Number	MABF284
Description	Anti-RIG1 Antibody, clone 42
Alternate Names	Retinoic acid receptor responder protein 3 HRAS-like suppressor 4 HRSL4 RAR-responsive protein TIG3 Retinoid-inducible gene 1 protein Tazarotene-induced gene 3 protein
Background Information	RIG1 is a cytoplasmically bound enzyme that exhibits phospholipase 1/2 activity and catalyzes the hydrolysis of various important membrane lipids including phosphatidylcholine and phosphatidylethanolamine containing lipids. RIG1 mimics PLA1/2 activities in many tissues and is widely expressed. Recent research has shown that RIG1 also functions as a cytoplasmic pattern receptor that detects viral RNA and acts as a cellular sensor for viral infection, which in turn can activate the proinflammatory response and the production of type-1 interferons against the infection.

References

Product Information
Format	Purified
Presentation	Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level	MQ100

Applications
Application	This Anti-RIG1 Antibody, clone 42 is validated for use in Western Blotting and Flow Cytometry for the detection of RIG1.
Key Applications	Western Blotting Flow Cytometry
Application Notes	Flow Cytometry Analysis: 0.25 µg of this antibody from a representative lot detected RIG1 in 1X10E6 THP-1 cells.

Biological Information
Immunogen	Recombinant protein corresponding to human RIG1.
Clone	42
Concentration	Please refer to lot specific datasheet.
Host	Mouse
Isotype	IgG1κ
Species Reactivity	Human
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NP_004576
Gene Symbol	RARRES3 RIG1 TIG3
Purification Method	Protein G Purified
UniProt Number	Q9UL19
Molecular Weight	~17 kDa observed

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by Western Blotting in THP-1 cell lysate. Western Blotting Analysis: 2.0 µg/mL of this antibody detected RIG1 in 10 µg of THP-1 cell lysate.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at 2-8°C from date of receipt.

Packaging Information
Material Size	100 µg

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
MABF284	04055977112122

Documentation

Anti-RIG1 Antibody, clone 42 MSDS

职位
物料安全数据表 (MSDS)

Anti-RIG1 Antibody, clone 42 分析证书

标题	批号
Anti-RIG1, clone 42	Q2475117
Anti-RIG1, clone 42 - 3499830	3499830
Anti-RIG1, clone 42 - 3996374	3996374

种类

Life Science Research > Antibodies and Assays > Primary Antibodies

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